Results 81 to 90 of about 41,464 (303)
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Spontaneous helical alignment of smooth muscle cells is induced within resistance‐vessel‐sized channels patterned within a hydrogel. The extent of the cells’ orientation angle is dependent on the presence and composition of ECM proteins lining the channel wall and cell seeding density.
Victoria D. Vest +5 more
wiley +1 more source
Non-equilibrium stochastic dynamics of open ion channels [PDF]
We present and discuss a modified version of reaction rate theory (RRT) to describe the passage of a positive ion through a biological ion channel. It takes explicit account of the non-equilibrium nature of the permeation process. Unlike traditional RRT,
Kaufman, Igor +10 more
core
Early ADMET profiling of anti-inflammatory alkaloids using validated LC-MS/MS methods [PDF]
Natural products provide an important and unique source of new lead compounds for drug discovery. Approximately 50% of all new chemical entities are inspired by nature.
Jähne, Evelyn
core +1 more source
Integrated Visible Light and Oxidant Protection Through Multifunctional Sunscreens
High‐energy visible radiation (HEVR), although less energetic than UV light, penetrates deeper into the skin and contributes to photoaging, pigmentation disorders, and oxidative stress. The development of new HEVR‐targeted filters, therefore, represents not only a scientific challenge but also a pressing public health and cosmetic industry need.
Beatriz Peñín +3 more
wiley +1 more source
The present work attempted to produce thick zirconia coatings formed by micro-arc oxidation as a hydrogen permeation barrier on zirconium hydride alloy.
Wen Ma +7 more
core +1 more source
We develop a covalent organic framework‐loaded Traditional Chinese Medicine monomer nanodrug delivery system (ISL@bCOF) via boron‐oxygen bonds, a smart response to glucose for delivering AI‐driven isoliquiritigenin (ISL) targeting ZBP1. This dynamic release mechanism, combined with transdermal delivery technology via potent microneedles, can modulate ...
Menghan Zhou +9 more
wiley +1 more source
Permeation Barrier Coatings for the Helical Heat Exchanger [PDF]
A permeation barrier coating was specified for the Helical Heat Exchanger (HHE) to minimize contamination through emissions and/or permeation into the nitrogen system for ALARA reasons.
Korinko, P.S.
core +1 more source
Synthesis and Analgesic Activity Evaluation of Some Agmatine Derivatives
A series of N,N’-disubstituted-2-nitroethene-1,1-diamine and N,N’-disubstituted- N’’-cyanoguanidine derivatives were prepared and evaluated for in vivo analgesic activity.
Song Li +8 more
doaj +1 more source
Natural Biomaterials for Osteochondral Repair: From Source to Strategy
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu +5 more
wiley +1 more source

