Results 31 to 40 of about 100,349 (273)

Input parameters for manuscript "Understanding drug skin permeation enhancers using Molecular Dynamics Simulation"

, 2023
Input parameters used for Gromacs simulations in publication with title: "Understanding drug skin permeation enhancers using Molecular Dynamics ...
Lars, Magnus, Christian, Erik
core   +1 more source

COMBINED EFFECT OF CHEMICAL ENHANCERS AND ULTRASOUND ON THE SKIN PERMEATION OF CAFFEINE [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2008
The combined effect of 800 kHz ultrasound with 2W/cm2 intensity and chemical enhancers on the skin permeation of caffeine was investigated using excised ear rabbit skin.
Thanaa E. Borg
doaj   +1 more source

Enhanced Transdermal Delivery of Bisoprolol Hemifumarate via Combined Effect of Iontophoresis and Chemical Enhancers: Ex Vivo Permeation/In Vivo Pharmacokinetic Studies

Pharmaceutics, 2021
Bisoprolol hemifumarate (BH) is an antihypertensive drug that is used as first-line treatment for chronic hypertension and angina pectoris. Our study was performed to enhance the transdermal delivery of BH, a hydrophilic drug active with high molecular ...
Mahmoud H. Teaima, Mohamed Azmi Ahmed Mohamed, Randa Tag Abd El Rehem, Saadia A. Tayel, Mohamed A. El-Nabarawi, Shahinaze A. Fouad   +5 more
doaj   +1 more source

Altered Skin Permeation of Finasteride Using Clove Oil, Urea, and Lyophilized Powder of Grape Seed Extract [PDF]

Advanced Pharmaceutical Bulletin, 2023
Purpose: Finasteride is a 5-alpha reductase inhibitor used to treat hair loss and acne. The skin permeation of finasteride is one of the main challenges associated with dermal drug delivery.
Anayatollah Salimi, Hamid Mohammad Soleymani, Saeed Mohammad Soleymani   +2 more
doaj   +1 more source

Modelling the effect of mixture components on permeation through skin [PDF]

, 2010
A vehicle influences the concentration of penetrant within the membrane, affecting its diffusivity in the skin and rate of transport. Despite the huge amount of effort made for the understanding and modelling of the skin absorption of chemicals, a ...
E.G. Samaras, J.E. Riviere, Ghafourian, Taravat, Samaras, Eleftherios G., J E Riviere (16236797), E G Samaras (16236791), Riviere, Jim E., J.D. Brooks, Taravat Ghafourian (4466557), J D Brooks (16236794), Brooks, James D., T. Ghafourian   +11 more
core   +1 more source

THE EFFECT OF PERMEATION ENHANCERS ON THE PHYSICAL CHARACTERS AND PERMEATION PARAMETERS OF BUCCOADHESIVE CHLORPHENIRAMINE MALEATE TABLETS

Zagazig Journal of Pharmaceutical Sciences, 2006
The buccoadhesive tablets of Chlorpheniramine Maleate (CPM) were prepared using bioadhesive polymers as sodium Carboxymethy1 cellulose (NACMC), sodium alginate. Hydroxyethy1cellulose (HEC).
Alaa Kassem , Maha Marzouk , Amal Ammar , Ghada Elosaily   +3 more
doaj   +1 more source

Permeability Enhancement of Methotrexate Transdermal Gel using Eucalyptus oil, Peppermint Oil and Olive Oil(Conference Paper )#

Iraqi Journal of Pharmaceutical Sciences, 2022
Objective: the idea of this study to improve transdermal permeability of Methotrexate using eucalyptus oil, olive oil and peppermint oil as enhancers. Method: eucalyptus oil (2% and 4%), peppermint oil (2% and 4%) and olive oil (2% and 4%) all used as ...
Jamal Ali Ashoor, Jinan M. Mohsin, Hussein Mohammed Mohsin, Basam W. Mahde, Mowafaq M. Gareeb   +4 more
doaj   +1 more source

Oral delivery of macromolecules formulated with permeation enhancers

, 2022
Therapeutic macromolecules including peptides, proteins, and nucleotide-based ones (such as antisense oligonucleotides and RNAs) have great potential as drug candidates.
Berg, Staffan
core   +2 more sources

Brush border membrane vesicle and Caco-2 cell line: Two experimental models for evaluation of absorption enhancing effects of saponins, bile salts, and some synthetic surfactants

Journal of Advanced Pharmaceutical Technology & Research, 2016
The aim of this study was to investigate the influence of absorption enhancers in the uptake of hydrophilic compounds. The permeation of the two hydrophilic drug models gentamicin and 5 (6)-carboxyfluorescein (CF) across the brush border membrane ...
Eskandar Moghimipour, Sayyed Abolghassem Sajadi Tabassi, Mohammad Ramezani, Somayeh Handali, Raimar Lobenberg   +4 more
doaj   +1 more source

Ion Pairs for Transdermal and Dermal Drug Delivery: A Review

Pharmaceutics, 2021
Ion pairing is a strategy used to increase the permeation of topically applied ionised drugs. Formation occurs when the electrostatic energy of attraction between oppositely charged ions exceeds their mean thermal energy, making it possible for them to ...
Mignon Cristofoli, Chin-Ping Kung, Jonathan Hadgraft, Majella E. Lane, Bruno C. Sil   +4 more
doaj   +1 more source