Novel Chemical Permeation Enhancers for Transdermal Drug Delivery
Transdermal drug delivery has been accepted as a potential non-invasive route of drug administration, with advantages of prolonged therapeutic action, decreased side effect, easy use and better patient compliance.
Xiaochang Liu, Peng Quan
exaly +4 more sources
This study aimed to systematically compare licochalcone A (LicA) and glabridin (Gla) (whitening agents) release and permeation from Carbomer 940 (CP) hydrogels with different enhancers, and evaluate the relationship between the quantitative enhancement ...
Zhuxian Wang +11 more
doaj +2 more sources
Effect of permeation enhancers on the penetration mechanism of transfersomal gel of ketoconazole
The aim of the present research work was to investigate the potential of transfersome formulations for transdermal delivery of Ketoconazole (KTZ). KTZ is a broad-spectrum antifungal agent that is active against a wide variety of fungi and yeasts.
Reshmy Rajan, Deepa T Vasudevan
doaj +2 more sources
PHARMACEUTICAL WORLD OF PERMEATION ENHANCERS [PDF]
The drugs with poor solubility results in delayed absorption which consequently affects the bioavailability. There are many drugs which are having good therapeutic value but not used commercially because of this reason. The permeation enhancers are therefore being utilized to counter this problem.
MANISH KUMAR, DEEPAK PRASHAR
core +4 more sources
Permeation Enhancers for Enhanced Topical Delivery of Pharmaceutical and Cosmeceutical Products
Background: Topical cosmetic and therapeutic agents are often limited in their effectiveness due to the skin barrier, which hinders the permeation of active ingredients.
Maha N. Abu Hajleh +5 more
doaj +2 more sources
Potential of essential oils as alternative permeation enhancers for transdermal delivery
Transdermal drug delivery plays a significant part in the drug delivery system when compared to other routes of drug administration. The function of the stratum corneum (SC) is a barrier.
Jayshree Mahanty +4 more
doaj +2 more sources
Effect of permeation enhancers on in vitro release and transdermal delivery of lamotrigine from Eudragit®RS100 polymer matrix-type drug in adhesive patches [PDF]
The drug-in-adhesive (DIA)-type matrix patches of lamotrigine are developed using variable permeation enhancers (oleic acid, PG, lemon oil and aloe vera), and drug in vitro release and its permeation are evaluated.
Ifrah Jafri +3 more
doaj +2 more sources
A Systematic Quantitative Evaluation of Permeation Enhancement Window: Transdermal Permeation Enhancing Dynamics Establishment and Molecular Mechanisms Characterization of Permeation Enhancer [PDF]
At present, transdermal permeation enhancing dynamics studies on permeation enhancers are still limited. In this study, these dynamics were established based on the content of enhancer Plurol Oleique CC in skin (CPOCC) and the increment of drug permeation amount (ΔQ).
Jiuheng Ruan +5 more
openaire +2 more sources
Overlook of chiral consideration in transdermal drug delivery increases administrated dose and risk of side effects, decreasing therapeutical effects. To improve the transdermal delivery efficiency of eutomer, this work focused on investigating the law ...
Yang Zhang +9 more
doaj +1 more source
Application of Permeation Enhancers in Oral Delivery of Macromolecules: An Update [PDF]
Luca Casettari +2 more
exaly +2 more sources

