Results 121 to 130 of about 405,825 (324)
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
forqs: Forward-in-time Simulation of Recombination, Quantitative Traits, and Selection [PDF]
forqs is a forward-in-time simulation of recombination, quantitative traits, and selection. It was designed to investigate haplotype patterns resulting from scenarios where substantial evolutionary change has taken place in a small number of generations ...
Kessner, Darren, Novembre, John
core
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Permissive nominal terms [PDF]
We present a simplified version of nominal terms with improved properties. Nominal terms are themselves a version of first-order terms, adapted to provide primitive support for names, binding, capturing substitution, and alpha-conversion.
Dowek, Gilles +2 more
core +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Permissive Hypotension and Permissive Haemorrhage – Are They Necessary Evils of Trauma?
Mansoor Khan, Boris Kessel
doaj +1 more source
Perceived Parenting Styles and Psycho-social Wellbeing of Nigerian Adolescents [PDF]
The influence of parenting styles on the psychosocial wellbeing of Nigerian adolescents is yet to be given adequate research attention. This study bridges the gap in knowledge.
Akinnawo, Ebernezer O.
core
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Student learning with permissive and restrictive cell phone policies: A classroom experiment
Based on Finn and Ledbetter’s (2013; 2014) work regarding classroom technology policies, this experimental study examined the implementation of a permissive and a restrictive cellular phone policy in two sections of a public speaking course, and the ...
Alexander Lancaster
doaj +1 more source
Feedback control logic synthesis for non safe Petri nets
This paper addresses the problem of forbidden states of non safe Petri Net (PN) modelling discrete events systems. To prevent the forbidden states, it is possible to use conditions or predicates associated with transitions.
Alla, Hassane, Dideban, Abbas
core +3 more sources

