Results 81 to 90 of about 192,401 (288)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Permissive Effects of Nuclear Taboo

open access: yes, 2023
Does stigmatization of nuclear weapons increase public support for greater use of non-nuclear weapons? One hypothesized implication of the nuclear taboo is that it also has permissive effects and has legitimated greater, more destructive use of ...
Naomi Egel
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

PERMISSION TO WRITE

open access: yesPhilologia hispalensis, 2020
In this narrative auto-ethnographic paper, I experiment with a version of “post-academic” writing. I explore how I could improve and develop my craft as a narrative inquirer and strengthen my written voice as an expression of my practitioner-researcher autonomy. I tell the story of two writers, myself and Laura, my student, by bringing us as characters
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The clinical effectiveness of permissive hypotension in blunt abdominal trauma with hemorrhagic shock but without head or spine injuries or burns: a systematic review

open access: yes, 2012
Abdulrahman AlsawadiColchester Hospital University NHS Foundation Trust, Colchester, Essex, United KingdomBackground: Trauma is a major cause of death and disability.
Alsawadi A
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Perilaku Cyberbullying pada Remaja: Ditinjau dari Anger Management dan Pola Asuh Permisif

open access: yesPsikologika: Jurnal Pemikiran dan Penelitian Psikologi, 2018
Cyberbullying has been developed in recent years. It has negative impacts for its victims such as low self esteem, anxiety, and depression. This study aims to examine the relationship between anger management and permissive parenting patterns with ...
Moh Aminullah   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

LS 203 - Permissive Society [PDF]

open access: yes, 1980
Audio recording of LS 203 - Permissive Society by Landon Brady Saunders.
Saunders, Landon Brady
core  

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