Results 91 to 100 of about 382,738 (264)
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Parse Journal, 2023 The greedy and unstoppable bulldozer of runaway globalisation has led to unprecedented economic growth in the world since the 1990s, but at a cost. Local realities, practices and knowledges are being smothered, and ecosystems worldwide are becoming more ...
Thomas Hylland Eriksen
doaj
Сучасні інформаційні системи, 2019 Based on the analysis of a group of two-bit two-operand operations of strict stable cryptographic coding, the relations between direct and inverse operations are established and formalized and their correctness is proved.
Volodymir Rudnitsky +4 more
doaj +1 more source
Journal of the Royal Statistical Society Series B: Statistical Methodology, 1968 Summary The problem of generating random permutations of the integers 1, 2, …, n arises, for example, when sampling a randomization distribution and when tables of permutations are required for application to experimental design. An algorithm is described which minimizes the amount of randomization necessary to generate a random ...
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2016 We suggest the procedure of a direct enumeration of outcomes of the scheme with definite discipline of their enumeration. On this base we conduct the invesnigations in the follouing directios: finding the common number of the outcomes of the scheme ...
Natalya Enatskaya
doaj +1 more source
Permutable Periodic Transformations [PDF]
Proceedings of the National Academy of Sciences, 1944 Not ...
openaire +2 more sources
Equivalence Classes of Permutations Modulo Replacements Between 123 and Two-Integer Patterns [PDF]
, 2013 We explore a new type of replacement of patterns in permutations, suggested by James Propp, that does not preserve the length of permutations. In particular, we focus on replacements between 123 and a pattern of two integer elements.
Fazel-Rezai, Vahid
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source