Results 91 to 100 of about 476,988 (354)

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Some equinumerous pattern-avoiding classes of permutations [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2005
Suppose that p,q,r,s are non-negative integers with m=p+q+r+s. The class X(p,q,r,s) of permutations that contain no pattern of the form α β γ where |α |=r, |γ |=s and β is any arrangement of \1,2,\ldots,p\∪ \m-q+1, m-q+2, \ldots,m\ is considered.
M. D. Atkinson
doaj   +1 more source

Longest Common Separable Pattern between Permutations [PDF]

open access: yes, 2007
In this article, we study the problem of finding the longest common separable pattern between several permutations. We give a polynomial-time algorithm when the number of input permutations is fixed and show that the problem is NP-hard for an arbitrary ...
Bouvel, Mathilde   +2 more
core   +5 more sources

Pseudorandom permutation

open access: yesJournal of Computational and Applied Mathematics, 2002
AbstractA number-theoretical approach to the permutation of a sequence of objects performed by means of a linear congruential generator of pseudorandom numbers is presented. A sufficient condition is found for obtaining permutations with the property that each object definitely abandons its initial position.
De Matteis, A, Pagnutti, S
openaire   +3 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

An efficient crossover design for thorough QT studies / Ein effizientes Crossover-Design für klinische Studien zur Untersuchung des QT-Intervalls

open access: yesGMS Medizinische Informatik, Biometrie und Epidemiologie, 2010
Background: Thorough QT studies are typically a requirement of the clinical development program for new investigational drugs. These studies are a major cost factor in early development.
Ring, Arne   +3 more
doaj  

The possibility of applying calculation based on queuing theory with the aim of real-time control

open access: yesСистемный анализ и прикладная информатика, 2019
Possibilities of using mathematical models of the theory of queues for the purpose of control of processes of discrete productions modeled by it in real time are investigated.
V. I. Kudriavtsev, О. F. Zirko
doaj   +1 more source

Minimal complexity of equidistributed infinite permutations

open access: yes, 2016
An infinite permutation is a linear ordering of the set of natural numbers. An infinite permutation can be defined by a sequence of real numbers where only the order of elements is taken into account.
Avgustinovich, Sergey V.   +2 more
core   +2 more sources

On permutation labeling

open access: yesJournal of the Egyptian Mathematical Society, 2011
AbstractWe determine all permutation graphs of order ⩽9. We prove that every bipartite graph of order ⩽50 is a permutation graph. We convert the conjecture stating that “every tree is a permutation graph” to be “every bipartite graph is a permutation graph”.
Mohamed Seoud, M.A. Salim
openaire   +3 more sources

The depth of a permutation [PDF]

open access: yesJournal of Combinatorics, 2015
For the elements of a Coxeter group, we present a statistic called depth, defined in terms of factorizations of the elements into products of reflections. Depth is bounded above by length and below by the average of length and reflection length. In this article, we focus on the case of the symmetric group, where we show that depth is equal to sum_i max{
T. Kyle Petersen, Bridget Eileen Tenner
openaire   +2 more sources

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