Results 71 to 80 of about 406,083 (268)
Small Superpatterns for Dominance Drawing
We exploit the connection between dominance drawings of directed acyclic graphs and permutations, in both directions, to provide improved bounds on the size of universal point sets for certain types of dominance drawing and on superpatterns for certain ...
Bannister, Michael J. +2 more
core +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Longest increasing subsequences of random colored permutations [PDF]
We compute the limit distribution for (centered and scaled) length of the longest increasing subsequence of random colored permutations. The limit distribution function is a power of that for usual random permutations computed recently by Baik, Deift ...
Borodin, Alexei
core +1 more source
Counting permutations where the difference between entries located r places apart can never be s (for any given positive integers r and s) [PDF]
George Spahn, Doron Zeilberger
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
This article studies the poset of simple permutations with respect to the pattern involvement. We specify results on critically indecomposable posets obtained by Schmerl and Trotter to simple permutations and prove that if $\sigma, \pi$ are two simple ...
Adeline, Pierrot, Dominique, Rossin
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The greedy and unstoppable bulldozer of runaway globalisation has led to unprecedented economic growth in the world since the 1990s, but at a cost. Local realities, practices and knowledges are being smothered, and ecosystems worldwide are becoming more ...
Thomas Hylland Eriksen
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

