Results 71 to 80 of about 407,922 (313)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
GMS Medizinische Informatik, Biometrie und Epidemiologie, 2010 Background: Thorough QT studies are typically a requirement of the clinical development program for new investigational drugs. These studies are a major cost factor in early development.
Ring, Arne +3 more
doaj
The possibility of applying calculation based on queuing theory with the aim of real-time control
Системный анализ и прикладная информатика, 2019 Possibilities of using mathematical models of the theory of queues for the purpose of control of processes of discrete productions modeled by it in real time are investigated.
V. I. Kudriavtsev, О. F. Zirko
doaj +1 more source
Permutations avoiding an increasing number of length-increasing forbidden subsequences [PDF]
Discrete Mathematics & Theoretical Computer Science, 2000 A permutation π is said to be τ -avoiding if it does not contain any subsequence having all the same pairwise comparisons as τ . This paper concerns the characterization and enumeration of permutations which avoid a set F^j of subsequences increasing ...
Elena Barcucci +3 more
doaj +1 more source
The enumeration of permutations avoiding 2143 and 4231 [PDF]
, 2011 We enumerate the pattern class Av(2143, 4231) and completely describe its permutations.
Albert, M. H. +2 more
core +2 more sources
Coherent random permutations with record statistics
, 2006 Random permutations with distribution conditionally uniform given the set of record values can be generated in a unified way, coherently for all values of $n$.
Gnedin, Alexander
core +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Some new facts about group 𝒢 generated by the family of convergent permutations
Open Mathematics, 2017 The aim of this paper is to present some new and essential facts about group 𝒢 generated by the family of convergent permutations, i.e. the permutations on ℕ preserving the convergence of series of real terms.
Wituła Roman +2 more
doaj +1 more source
Some equinumerous pattern-avoiding classes of permutations [PDF]
Discrete Mathematics & Theoretical Computer Science, 2005 Suppose that p,q,r,s are non-negative integers with m=p+q+r+s. The class X(p,q,r,s) of permutations that contain no pattern of the form α β γ where |α |=r, |γ |=s and β is any arrangement of \1,2,\ldots,p\∪ \m-q+1, m-q+2, \ldots,m\ is considered.
M. D. Atkinson
doaj +1 more source
Longest increasing subsequences of random colored permutations [PDF]
, 1999 We compute the limit distribution for (centered and scaled) length of the longest increasing subsequence of random colored permutations. The limit distribution function is a power of that for usual random permutations computed recently by Baik, Deift ...
Borodin, Alexei
core +1 more source