Results 71 to 80 of about 382,738 (264)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
GMS Medizinische Informatik, Biometrie und Epidemiologie, 2010 Background: Thorough QT studies are typically a requirement of the clinical development program for new investigational drugs. These studies are a major cost factor in early development.
Ring, Arne +3 more
doaj
Permutations avoiding an increasing number of length-increasing forbidden subsequences [PDF]
Discrete Mathematics & Theoretical Computer Science, 2000 A permutation π is said to be τ -avoiding if it does not contain any subsequence having all the same pairwise comparisons as τ . This paper concerns the characterization and enumeration of permutations which avoid a set F^j of subsequences increasing ...
Elena Barcucci +3 more
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On the Decoding of Polar Codes on Permuted Factor Graphs
, 2018 Polar codes are a channel coding scheme for the next generation of wireless communications standard (5G). The belief propagation (BP) decoder allows for parallel decoding of polar codes, making it suitable for high throughput applications.
Doan, Nghia +3 more
core +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Some new facts about group 𝒢 generated by the family of convergent permutations
Open Mathematics, 2017 The aim of this paper is to present some new and essential facts about group 𝒢 generated by the family of convergent permutations, i.e. the permutations on ℕ preserving the convergence of series of real terms.
Wituła Roman +2 more
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Some equinumerous pattern-avoiding classes of permutations [PDF]
Discrete Mathematics & Theoretical Computer Science, 2005 Suppose that p,q,r,s are non-negative integers with m=p+q+r+s. The class X(p,q,r,s) of permutations that contain no pattern of the form α β γ where |α |=r, |γ |=s and β is any arrangement of \1,2,\ldots,p\∪ \m-q+1, m-q+2, \ldots,m\ is considered.
M. D. Atkinson
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Paweł Hendrich’s Emergent Sound System
Musicology Today, 2015 Paweł Hendrich’s compositions can be compared to macrocrystals - solids composed of numerous small and identical elements, constructed in accordance with a strict pattern.
Hendrich Paweł, Stefański Krzysztof
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