Results 81 to 90 of about 476,988 (354)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Polyominoes determined by involutions [PDF]
Discrete Mathematics & Theoretical Computer Science, 2008 A permutomino of size n is a polyomino determined by particular pairs $(\pi_1, \pi_2)$ of permutations of length $n$, such that $\pi_1(i) \neq \pi_2(i)$, for $1 \leq i \leq n$.
Filippo Disanto, Simone Rinaldi
doaj +1 more source
Pattern Count on Multiply Restricted Permutations [PDF]
, 2013 Previous work has studied the pattern count on singly restricted permutations. In this work, we focus on patterns of length 3 in multiply restricted permutations, especially for double and triple pattern-avoiding permutations. We derive explicit formulae
Zhao, Alina F. Y.
core
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
On the enumeration of column-convex permutominoes [PDF]
Discrete Mathematics & Theoretical Computer Science, 2011 We study the enumeration of \emphcolumn-convex permutominoes, i.e. column-convex polyominoes defined by a pair of permutations. We provide a direct recursive construction for the column-convex permutominoes of a given size, based on the application of ...
Nicholas R. Beaton +3 more
doaj +1 more source
Forum of Mathematics, Sigma, 2023 We introduce a new class of permutations, called web permutations. Using these permutations, we provide a combinatorial interpretation for entries of the transition matrix between the Specht and $\operatorname {SL}_2$ -web bases of the irreducible
Byung-Hak Hwang +2 more
doaj +1 more source
FEBS Letters, EarlyView.Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa +8 more
wiley +1 more source
Permutations avoiding an increasing number of length-increasing forbidden subsequences [PDF]
Discrete Mathematics & Theoretical Computer Science, 2000 A permutation π is said to be τ -avoiding if it does not contain any subsequence having all the same pairwise comparisons as τ . This paper concerns the characterization and enumeration of permutations which avoid a set F^j of subsequences increasing ...
Elena Barcucci +3 more
doaj +1 more source
Transport of patterns by Burge transpose
, 2020 We take the first steps in developing a theory of transport of patterns from Fishburn permutations to (modified) ascent sequences. Given a set of pattern avoiding Fishburn permutations, we provide an explicit construction for the basis of the ...
Cerbai, Giulio, Claesson, Anders
core
Simple permutations and pattern restricted permutations
Discrete Mathematics, 2005 AbstractA simple permutation is one that does not map any non-trivial interval onto an interval. It is shown that, if the number of simple permutations in a pattern restricted class of permutations is finite, the class has an algebraic generating function and is defined by a finite set of restrictions.
Michael H. Albert, Michael M. Atkinson
openaire +1 more source