Results 131 to 140 of about 853,052 (312)
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
FEBS Open Bio, EarlyView.Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
, 2017 a) Details of a malignant peritoneal effusion from a metastatic melanoma showing the pleomorphic features and pigment (PAPx400, LBC); b) Positivity for S100 in the same case (peritoneal effusion from a metastatic melanoma) on LBC (avidin-biotin ...
Tommaso Bizzarro (771703) +7 more
core +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
FEBS Open Bio, EarlyView.Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
Complete sequence and Clustal W alignment of identified peroxidase.
, 2013 CTP: cytosolic tryparedoxin peroxidase, P1: peroxidoxin1, SP: identified secretory peroxidase (Prx).
Nisha Singh (289415) +4 more
core +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Efeitos do probucol sobre a enzima glutationa peroxidase e sua relação com a neuroproteção [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Bioquímica, Florianópolis, 2012.O probucol é um composto antilipidêmico que apresenta propriedades anti-inflamatória e antioxidante em ...
Santos, Danúbia Bonfanti dos
core
, 1989 Peroxidase from kiwifruit (Actinidia chinensis) was extracted, precipitated with ammonium sulfate, and purified by DEAE-cellulose chromatography. Only one band with peroxidase activity with an estimated molecular weight of 40,00–42,000 daltons was found ...
Préstamo, Guadalupe
core +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Low-density lipoprotein cholesterol (LDL-C), commonly called “bad cholesterol”, is crucial to cardiovascular health. Increased LDL-C levels pose a substantial risk to human health.
Rattaporn Saenmuangchin (18247505) +5 more
core +1 more source
Advanced Functional Materials, EarlyView.Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou +6 more
wiley +1 more source