Results 111 to 120 of about 1,115,092 (313)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

A direct cerebello-telencephalic projection in an electrosensory mormyrid fish [PDF]

open access: yes, 1990
After injections of the posterior part of the lateral zone of the area dorsalis telencephali (Dlp) with either horseradish peroxidase or the newly available carbocyanine dye DiI, efferent cells were labeled in the valvula cerebelli of the mormyrid fish ...
Ebbesson   +22 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Polyamine, peroxidase activity and total protein content during storage of bird-of-paradise [PDF]

open access: yes, 2015
The present study was aimed to the determination of the effect of storage on some biochemical characteristics (PAs content, POX activity and total protein content) of flower tissue of bird-of-paradise.
de Moura, Fabiana Bezerra   +5 more
core  

Horizontal gene transfer contributed to the evolution of extracellular surface structures [PDF]

open access: yes, 2012
The single-cell layered ectoderm of the fresh water polyp Hydra fulfills the function of an epidermis by protecting the animals from the surrounding medium.
Altstätter, Johannes   +13 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Purification and characterization of peroxidase from date palm cv. Agwa fruits

open access: yesInternational Journal of Food Properties, 2019
Purification of peroxidase POII from date palm cv. Agwa fruits were carried out. The molecular mass of POII was 43 kDa. The broad pH optimum of POII at pH’s 6.0–7.0 was detected.
Mustafa Zeyadi
doaj   +1 more source

Growth and physiological attributes of blueberry seedlings inoculated with arbuscular mycorrhizal fungi [PDF]

open access: yesCiência Rural
: High-quality seedlings are one of the key factors in achieving high yield and precocity of blueberries. The inoculation of arbuscular mycorrhizal fungi (AMF) can enhance the development of seedlings in the nursery, ensuring more vigorous seedlings in a
Karla Siebert Sapelli   +7 more
doaj   +1 more source

Detection of antibodies to Sendai virus by enzyme-linked immunosorbent assay (ELISA) [PDF]

open access: yes, 1979
An enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies to Sendai virus, a paramyxovirus, is described. The assay was found to be about 20-fold more sensitive than the hemagglutination inhibition assay.
Avrameas   +17 more
core   +1 more source

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