Results 121 to 130 of about 1,072,450 (362)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Selenium in biology: Facts and medical perspectives [PDF]

, 2000
Several decades after the discovery of setenium as an essential trace element in vertebrates approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the 21(st) proteinogenic amino acid, selenocysteine, have been identified ...
Flohé, Leopold, Gärtner, Roland, Köhrle, Josef, Brigelius-Flohé, Regina, Böck, August, Meyer, Ortwin, Regina Brigelius-Flohé, Josef Köhrle, Ortwin Meyer, August Böck, Leopold Flohé, Roland Gärtner   +11 more
core   +2 more sources

Purification and characterization of peroxidase from date palm cv. Agwa fruits

International Journal of Food Properties, 2019
Purification of peroxidase POII from date palm cv. Agwa fruits were carried out. The molecular mass of POII was 43 kDa. The broad pH optimum of POII at pH’s 6.0–7.0 was detected.
Mustafa Zeyadi
doaj   +1 more source

Growth and physiological attributes of blueberry seedlings inoculated with arbuscular mycorrhizal fungi [PDF]

Ciência Rural
: High-quality seedlings are one of the key factors in achieving high yield and precocity of blueberries. The inoculation of arbuscular mycorrhizal fungi (AMF) can enhance the development of seedlings in the nursery, ensuring more vigorous seedlings in a
Karla Siebert Sapelli, Carine Rusin, Allison John de Sousa, Samuel Libani Santos, Fernando Braga Cristo, Juliano Tadeu Vilela de Resende, Adriana Knob, Renato Vasconcelos Botelho   +7 more
doaj   +1 more source

Accelerating the Peroxidase-Like Activity of Gold Nanoclusters at Neutral pH for Colorimetric Detection of Heparin and Heparinase Activity.

Analytical Chemistry, 2018
The peroxidase-like catalytic activity of gold nanoclusters (Au-NCs) is quite low around physiological pH, which greatly limits their biological applications.
Lianzhe Hu, Hong Liao, Lingyan Feng, Min Wang, Wensheng Fu   +4 more
semanticscholar   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Spatially resolved proteomic mapping in living cells with the engineered peroxidase APEX2

Nature Protocols, 2016
In this protocol, Hung et al. describe a method for performing cell compartment–specific proteomics for regions of interest using the engineered ascorbate peroxidase APEX2.
Victoria Hung, N. Udeshi, Stephanie S. Lam, Ken H. Loh, Kurt J. Cox, Kayvon Pedram, S. Carr, A. Ting   +7 more
semanticscholar   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Characterisation of a novel soybean candidate glutathione peroxidase/thioredoxin-dependent peroxidase in soybean exposed to osmotic/drought stress [PDF]

, 2012
>Magister Scientiae - MScDrought stress is a major contributor to reduced soybean crop yield and quality, this can however be mitigated by the plant’s antioxidant defence mechanisms.
Phillips, Kyle
core   +1 more source