Results 41 to 50 of about 1,103,570 (348)

The effect of different frequencies of ultrasound on the activity of horseradish peroxidase [PDF]

, 2018
Ultrasound technology has been studied by food researchers as an alternative method for thermal processing. The use of ultrasound as a way to inactivate and/or activate enzymes has been widely studied at low frequencies (20–40 kHz), however, little ...
Bremner, David H., Chu, Boon-Seang, Lemos, M. Adilia, Tsikrika, Konstantina   +3 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Effect of Water Content on the Thermal Inactivation Kinetics of Horseradish Peroxidase Freeze-Dried from Alkaline pH [PDF]

, 2001
The thermal inactivation of horseradish peroxidase freeze-dried from solutions of different pH (8, 10 and 11.5, measured at 25 C) and equilibrated to different water contents was studied in the temperature range from 110 to 150 C.
Hägerdal B., J. A. Saraiva, J. C. Oliveira, M. A. Lemos, Pizzocaro F., Van Loey A., Whitaker J. R.   +6 more
core   +2 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

A direct cerebello-telencephalic projection in an electrosensory mormyrid fish [PDF]

, 1990
After injections of the posterior part of the lateral zone of the area dorsalis telencephali (Dlp) with either horseradish peroxidase or the newly available carbocyanine dye DiI, efferent cells were labeled in the valvula cerebelli of the mormyrid fish ...
Ebbesson, Echteler, Erdl, Finger, Finger, Finger, Godement, Hanker, Lissman, Meek, Murakami, Murakami, Nieuwenhuys, Nieuwenhuys, Nieuwenhuys, Northcutt, Rooney, Russell, Szabo, Weston, Wullimann, Wullimann, Wullimann   +22 more
core   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Lipid composition of pea (Pisum sativum L.) and maize (Zea mays L.) root plasma membrane and membrane-bound peroxidase and superoxide dismutase [PDF]

Archives of Biological Sciences, 2007
Plasma membrane was isolated from roots of pea and maize plants and used to analyze POD and SOD isoforms, as well as lipid composition. Among lipids, phospholipids were the main lipid class, with phosphatidylcho­line being the most abundant individual ...
Kukavica Biljana, Quartacci M.F., Veljović-Jovanović Sonja, Navari-Izzo Flavia   +3 more
doaj   +1 more source

Computational approaches to shed light on molecular mechanisms in biological processes [PDF]

, 2006
Computational approaches based on Molecular Dynamics simulations, Quantum Mechanical methods and 3D Quantitative Structure-Activity Relationships were employed by computational chemistry groups at the University of Milano-Bicocca to study biological ...
Bonati, L, Bruschi, M, Cosentino, U, De Gioia, L, Fantucci, PC, Moro, G, Pandini, A, Papaleo, E, Pitea, D, Saracino, GAA, Zampella, G   +10 more
core   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

2014 REU Poster: Expression and Characterization of WT BMUL4434 from Burkholderia multivorans [PDF]

, 2014
Poster presentation at REU Summer's End Research Symposium, 2014, by REU participant Santina Johnson, Spring Hill College - Sean Elliott group, Kimberly Rizzolo lab mentorBacterial cytochrome c peroxidases (bCcPs) are di-heme enzymes that protect the ...
Johnson, Santina C.
core   +1 more source