Results 61 to 70 of about 801,061 (314)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Discovery and biodegradation characterization of polyethylene by Metabacillus niabensis

Frontiers in Microbiology
Polyethylene (PE), a type of plastic, is the primary contributor to persistent and prolonged environmental contamination. Plastic biodegradation is considered a promising approach to addressing current environmental issues.
Raj Kumar Sardar, Raj Kumar Sardar
doaj   +1 more source

Antioxidative Response of Various Cultivars of Sorghum (Sorghum bicolor L.) to Drought Stress [PDF]

Journal of Stress Physiology & Biochemistry, 2013
The present study was conducted with the aim to identify the response of antioxidant enzyme activities in seedlings of different sorghum cultivars under mannitol stress.
Gurpreet Singh, Nidhi Sharma
doaj  

Genomic Analysis of Stropharia rugosoannulata Reveals Its Nutritional Strategy and Application Potential in Bioremediation

Journal of Fungi, 2022
Stropharia rugosoannulata is not only a popular edible mushroom, but also has excellent potential in bioremediation. In this study, we present a high-quality genome of a monokaryotic strain of the S. rugosoannulata commercial cultivar in China.
Ying Yang, Guoliang Meng, Shujun Ni, Haifeng Zhang, Caihong Dong   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Remoção de fenol de águas residuárias utilizando método de polimerização e precipitação com enzima Horseradish peroxidase [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia QuímicaPoluentes aromáticos estão presentes em efluentes de diversos tipos de indústrias.
Montibeller, Mateus Mário
core  

Hitherto Unrecognized Fluorescence Properties of Coniferyl Alcohol

Molecules, 2010
We instituted a quasi-quality assurance program for demonstrating coniferyl alcohol’s fluorescence and fluorescence diminishment following enzymatic oxidation. The magnitude of diminishment was a measure of catalysis.
Anup Kumar Singh, Blake Alexander Simmons, Supratim Datta, Paul David Adams, Komandoor Elayavalli Achyuthan   +4 more
doaj   +1 more source

Peroxidase and peroxidase-oxidase activities of isolated human myeloperoxidases [PDF]

Biochemical Journal, 1987
Isolated neutrophils from healthy donors were used for the isolation of four highly purified forms of myeloperoxidase as determined by spectral (A430/A280 ratio 0.80-0.87) and enzyme-activity measurements. Although the myeloperoxidases exhibited different elution profiles on cation-exchange chromatography, gel filtration indicated similar relative ...
B E, Svensson, K, Domeij, S, Lindvall, G, Rydell   +3 more
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Descending pathways from hypothalamus to dorsal motor vagus and ambiguus nuclei in the rat [PDF]

, 1984
The anatomical pathways between the hypothalamus and cell groups of the lower medulla that are involved in the neural control of endocrine pancreas activity were investigated.
KUIPERS, F, Luiten, P. G. M., TERHORST, GJ, LUITEN, PGM, Kuipers, F.; id_orcid, Luiten, P.G.M.,, Horst, G.J. ter,, Kuipers, F.,, Kuipers, F., ter Horst, G. J.   +9 more
core   +1 more source