Results 61 to 70 of about 1,072,450 (362)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Discovery and biodegradation characterization of polyethylene by Metabacillus niabensis
Frontiers in MicrobiologyPolyethylene (PE), a type of plastic, is the primary contributor to persistent and prolonged environmental contamination. Plastic biodegradation is considered a promising approach to addressing current environmental issues.
Raj Kumar Sardar, Raj Kumar Sardar
doaj +1 more source
Antioxidative Response of Various Cultivars of Sorghum (Sorghum bicolor L.) to Drought Stress [PDF]
Journal of Stress Physiology & Biochemistry, 2013 The present study was conducted with the aim to identify the response of antioxidant enzyme activities in seedlings of different sorghum cultivars under mannitol stress.
Gurpreet Singh, Nidhi Sharma
doaj
Journal of Fungi, 2022 Stropharia rugosoannulata is not only a popular edible mushroom, but also has excellent potential in bioremediation. In this study, we present a high-quality genome of a monokaryotic strain of the S. rugosoannulata commercial cultivar in China.
Ying Yang +4 more
doaj +1 more source
Peroxidase and peroxidase-oxidase activities of isolated human myeloperoxidases [PDF]
Biochemical Journal, 1987 Isolated neutrophils from healthy donors were used for the isolation of four highly purified forms of myeloperoxidase as determined by spectral (A430/A280 ratio 0.80-0.87) and enzyme-activity measurements. Although the myeloperoxidases exhibited different elution profiles on cation-exchange chromatography, gel filtration indicated similar relative ...
B E, Svensson +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The preparation and characterisation of novel microperoxidase biocatalysts [PDF]
, 1987 Microperoxidases are haem oligopeptides, derived from the proteolytic digestion of cytochrome c, possessing peroxidase activity. They are termed "microperoxidases" in contrast to other relatively large peroxidases such as horseradish peroxidase.
Atkinson, Susan Lesley
core
Captopril molecules exhibit significant inhibitory effect for peroxidase-like nitrogendoped carbon dots [PDF]
, 2023 In this continuation, the inhibitory effect of captopril molecules on the nanozymatic activity of peroxidase-like nitrogen-doped carbon dots was evaluated.
Saeed Reza, Hormozi Jangi
core +1 more source
Hitherto Unrecognized Fluorescence Properties of Coniferyl Alcohol
Molecules, 2010 We instituted a quasi-quality assurance program for demonstrating coniferyl alcohol’s fluorescence and fluorescence diminishment following enzymatic oxidation. The magnitude of diminishment was a measure of catalysis.
Anup Kumar Singh +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source