Results 71 to 80 of about 853,052 (312)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Hitherto Unrecognized Fluorescence Properties of Coniferyl Alcohol

open access: yesMolecules, 2010
We instituted a quasi-quality assurance program for demonstrating coniferyl alcohol’s fluorescence and fluorescence diminishment following enzymatic oxidation. The magnitude of diminishment was a measure of catalysis.
Anup Kumar Singh   +4 more
doaj   +1 more source

Peroxidase and peroxidase-oxidase activities of isolated human myeloperoxidases [PDF]

open access: yesBiochemical Journal, 1987
Isolated neutrophils from healthy donors were used for the isolation of four highly purified forms of myeloperoxidase as determined by spectral (A430/A280 ratio 0.80-0.87) and enzyme-activity measurements. Although the myeloperoxidases exhibited different elution profiles on cation-exchange chromatography, gel filtration indicated similar relative ...
B E, Svensson   +3 more
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Textile Effluent Containing Azo Dyes Eco-Friendly Bioremediation using Lentinus sp. in a Packed-Bed Bioreactor with Pine Sawdust as an Organic Inducer

open access: yesUniversitas Scientiarum
Industrial textile effluents containing azo dyes pose a major environmental challenge due to their persistence and toxicity. This study evaluated the capacity of a native white-rot fungus (Lentinus sp.) to treat a real textile effluent polluted with an ...
Camila Gómez Garcés   +2 more
doaj   +1 more source

COMPARISON OF STRESS PROTEINS PARTICIPATION IN ADAPTATION MECHANISMS OF BAIKALIAN AND PALEARCTIC AMPHIPOD (AMPHIPODA; CRUSTACEA) SPECIES [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2006
The aim of the present study was a study of the influence different stressful factor on syntheses and activity of the stress proteins (HSP70, sHSP and peroxidase) of freshwater organism.
Timofeyev M.A   +6 more
doaj  

Effects of ageing on peroxidase activity and localization in radish (Raphanus sativus L.) seeds

open access: yesEuropean Journal of Histochemistry, 2010
Peroxidase activity was assayed in crude extracts of integument, cotyledons and embryo axis of radish seeds, deteriorated under accelerated ageing conditions.
A. Scialabba   +2 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

The evaluation of the antioxidant enzyme’s activity and activity of anaerobic glycolysis’ enzymes under gradual temperature increase in Baikal amphipod species Eulimnogammаrus marituji, E. maackii and Gmelinoides fasciatus [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2012
The aim of present study was the evaluation of the antioxidant enzyme’s activity and activity of anaerobic glycolysis enzymes under gradual temperature increase in Baikal amphipods species Eulimnogammarus marituji (Baz., 1945), E.
Axenov – Gribanov D. V., Lubyaga J. A.
doaj  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

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