Results 61 to 70 of about 51,934 (302)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Three differentially expressed basic peroxidases from wound-lignifying ¤Asparagus officinalis¤

, 2003
The activity of ionically bound peroxidases from an asparagus spear increased from 5-24 h post-harvest. Isoelectric focusing showed that the post-harvest increase of the total peroxidase activity was due to the increase of several distinct isoperoxidases.
Rasmussen, Søren K., Eckloff, Reinhard M.G., Rasmussen, S.K., Kristensen, Brian K., Holm, Kirsten B., Kristensen, B.K., Andreasen, P.H., Eckloff, R., Andreasen, Per H., Holm, K.B.   +9 more
core   +1 more source

High Auxin and High Phosphate Impact on RSL2 Expression and ROS-Homeostasis Linked to Root Hair Growth in Arabidopsis thaliana

Frontiers in Plant Science, 2018
Root hair size determines the surface area/volume ratio of the whole roots exposed to the nutrient and water pools, thereby likely impacting nutrient and water uptake rates.
Silvina Mangano, Silvina P. Denita-Juarez, Eliana Marzol, Cecilia Borassi, José M. Estevez   +4 more
doaj   +1 more source

Changes in the content of proteins and lipids and in the state of the antioxidant system in mutant forms of Amaranthus cruentus L.

Труды по прикладной ботанике, генетике и селекции, 2022
Background. One of the important indicators of the nutritional value of amaranth is the high content of protein and lipids in seeds. Hence, obtaining and identifying such forms of amaranth through breeding, so that they also possessed resistance to ...
R. M. Taipova, V. N. Nesterov, O. A. Rozentsvet, B. R. Kuluev   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Genome-Wide Characterization of Class III Peroxidases and Their Expression Profile During Mycorrhizal Symbiosis and Phosphorus Deprivation in Lettuce (Lactuca sativa L.)

Horticulturae
Lettuce cultivation requires high fertilizer inputs, which impact the environment and costs. Arbuscular mycorrhizal symbiosis (AMS) can reduce fertilizer use, enhance plant nutrition (especially phosphorus), and promote healthier plants.
Samuel Simoni, Marco Castellacci, Gabriele Usai, Ugo Rogo, Flavia Mascagni, Tommaso Giordani, Lucia Natali, Andrea Cavallini, Alberto Vangelisti   +8 more
doaj   +1 more source

Intraspecific differentiation of Reed Grass Calamagrostis arundinacea (L.) Roth (Poaceae) populations revealed by peroxidase allozymes

Acta Societatis Botanicorum Poloniae, 2011
The genetic Variation of Reed Grass Calamagrostis arundinacea (L.) Roth was investigated in 25 populations in various geographic regions of Poland. A total of 907 individuals were sampled for electrophoretic analysis of peroxidase loci (11 allozymes ...
Maria Krzakowa, Zbigniew Celka
doaj   +1 more source

Peroxidase and peroxidase-oxidase activities of isolated human myeloperoxidases [PDF]

Biochemical Journal, 1987
Isolated neutrophils from healthy donors were used for the isolation of four highly purified forms of myeloperoxidase as determined by spectral (A430/A280 ratio 0.80-0.87) and enzyme-activity measurements. Although the myeloperoxidases exhibited different elution profiles on cation-exchange chromatography, gel filtration indicated similar relative ...
B E, Svensson, K, Domeij, S, Lindvall, G, Rydell   +3 more
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Control of Postharvest Performance of the Lilacs ‘Andenken an Ludwig Spaeth’ Induced to Flower in Spring

Agriculture
Common lilac (Syringa vulgaris) is an important cut flower on the flower market. The process of forcing shrub is crucial for lilac availability for floristry for six months of the year: from November to April.
Ewa Skutnik, Aleksandra Łukaszewska, Diana Musiał, Agnieszka Zawadzińska, Piotr Salachna, Julita Rabiza-Świder   +5 more
doaj   +1 more source