Results 71 to 80 of about 81,876 (307)
Exercise redox biochemistry:conceptual, methodological and technical recommendations [PDF]
, 2017 Exercise redox biochemistry is of considerable interest owing to its translational value in health and disease. However, unaddressed conceptual, methodological and technical issues complicate attempts to unravel how exercise alters redox homeostasis in ...
Bailey, Damian M. +3 more
core +11 more sources
The Acari Hypothesis, V: deciphering allergenicity
Frontiers in AllergyThe Acari Hypothesis posits that acarians, i.e., mites and ticks, are operative agents of allergy. It derived from observations that allergens are molecular elements of acarians or acarian foodstuffs.
Andrew C. Retzinger +1 more
doaj +1 more source
Molecules, 2015 “Artificial enzymes”, a term coined by Breslow for enzyme mimics is an exciting and promising branch of biomimetic chemistry aiming to imitate the general and essential principles of natural enzymes using a variety of alternative materials including ...
Bhaskar Garg +2 more
doaj +1 more source
Resonance Raman Spectroscopy Reveals pH-Dependent Active Site Structural Changes of Lactoperoxidase Compound 0 and Its Ferryl Heme O–O Bond Cleavage Products [PDF]
, 2014 The first step in the enzymatic cycle of mammalian peroxidases, including lactoperoxidase (LPO), is binding of hydrogen peroxide to the ferric resting state to form a ferric-hydroperoxo intermediate designated as Compound 0, the residual proton ...
Kincaid, James R. +3 more
core +3 more sources
Engineering Ascorbate Peroxidase Activity into Cytochrome c Peroxidase [PDF]
Biochemistry, 2008 Cytochrome c peroxidase (CCP) and ascorbate peroxidase (APX) have very similar structures, and yet neither CCP nor APX exhibits each other's activities with respect to reducing substrates. APX has a unique substrate binding site near the heme propionates where ascorbate H-bonds with a surface Arg and one heme propionate (Sharp et al. (2003) Nat. Struct.
Yergalem T, Meharenna +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecules, 2019 DyP-type peroxidases are heme-containing enzymes that have received increasing attention over recent years with regards to their potential as biocatalysts.
Mohamed H. Habib +2 more
doaj +1 more source
Anti-atherogenic properties associated with the antioxidant activity from the hydrophilic extracts of Halimeda incrassata (Chlorophyta, Bryopsidales) [PDF]
, 2017 Seaweeds are a source of natural antioxidants having potential application in oxidative stress and associated diseases. In this work, anti-atherogenic properties associated with the antioxidant activity from the hydrophilic extracts of Halimeda ...
Claudina, Zaldívar-Munoz +8 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Plant, Soil and Environment, 2010 Ravenelia esculenta Naras. and Thirum. is a rust fungus which infects Acacia eburnea Willd. producing hypertrophy in the infected organs. We analysed the changes in the reaction patterns of peroxidase from the tissues at progressive disease stages ...
A.A. Kuvalekar, K.R. Gandhe
doaj +1 more source