Results 51 to 60 of about 439,678 (239)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Aetiology and treatment of epidermal depigmentory disorder in humans [PDF]

open access: yes, 2012
The epidermal depigmentary trigger in humans at post-natal level may occur with the toxification of skin organ with the endogenously produced melanocytotoxic hydrogen peroxide and subsequent formation of hydrogen peroxide- melanolipoprotein conjugate ...
S. S. Sawhney
core   +1 more source

The degree of tooth colour change after using different concentrations of carbamide peroxide [PDF]

open access: yesScripta Medica, 2019
Background: Depending on the cause of discoloration, bleaching materials and other factors, vital dental bleaching techniques may be professional (in-office dental bleaching), at-home night-guard bleaching and combined.
Knežević Nataša   +6 more
doaj  

Crystal structure of rubidium peroxide ammonia disolvate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2017
The title compound, Rb2O2·2NH3, has been obtained as a reaction product of rubidium metal dissolved in liquid ammonia and glucuronic acid. As a result of the low-temperature crystallization, a disolvate was formed.
Tobias Grassl, Nikolaus Korber
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Hydrogen Peroxide in Adaptation [PDF]

open access: yesOxidative Medicine and Cellular Longevity, 2012
The perception of the roles of H2O2 in living systems has come a long way, transcending from H2O2 being considered as (i) exclusively damaging; (ii) a necessary evil “unwanted but an inevitable product of aerobic metabolism”; (iii) important for specific biological processes that involve ROS aggressiveness, such as the battle of the innate immune ...
David R. Jones   +2 more
openaire   +2 more sources

Vibrational overtone initiated unimolecular dissociation of HOCH_2OOH and HOCD_2OOH: Evidence for mode selective behavior [PDF]

open access: yes, 2008
The vibrational overtone induced unimolecular dissociation of HMHP (HOCH2OOH) and HMHP-d2 (HOCD2OOH) into OH and HOCH2O (HOCD2O) fragments is investigated in the region of the 4nuOH and 5nuOH bands.
Fry, Julie L.   +4 more
core  

Purification of degummed crude sunflower oil with selected metal-organic frameworks as adsorbents

open access: yesGrasas y Aceites, 2019
The aims of this study were to investigate the effectiveness of seven metal-organic frameworks (MOFs) as adsorbents for the purification of crude degummed sunflower oil, and to compare their effectiveness with three natural clays.
E. Yılmaz, A. K. Erden
doaj   +1 more source

Obesity and Fatty Acids Promote Mitochondrial Translocation of STAT3 Through ROS-Dependent Mechanisms

open access: yesFrontiers in Aging, 2022
Obesity promotes the onset and progression of metabolic and inflammatory diseases such as type 2 diabetes. The chronic low-grade inflammation that occurs during obesity triggers multiple signaling mechanisms that negatively affect organismal health.
Rachel Conway   +11 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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