Results 251 to 260 of about 60,989 (305)
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Peroxides and Peroxide-Degrading Enzymes in the Thyroid
Antioxidants & Redox Signaling, 2008Iodination of thyroglobulin is the key step of thyroid hormone biosynthesis. It is catalyzed by thyroid peroxidase and occurs within the follicular space at the apical plasma membrane. Hydrogen peroxide produced by thyrocytes as an oxidant for iodide may compromise cellular and genomic integrity of the surrounding cells, unless these are sufficiently ...
Ulrich, Schweizer +2 more
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Radiation Research Supplement, 1963
The role of peroxides, produced by radiation or oxidative processes in metabolism, in the production of mutations is reviewed. Results are reported from studies on living cells immersed in peroxides modified in various ways. Results are used to postulate the action of internally formed peroxides on the hereditary substance. It is concluded that it will
O, WYSS, C, WIESEN, G E, SCHAIBERGER
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The role of peroxides, produced by radiation or oxidative processes in metabolism, in the production of mutations is reviewed. Results are reported from studies on living cells immersed in peroxides modified in various ways. Results are used to postulate the action of internally formed peroxides on the hereditary substance. It is concluded that it will
O, WYSS, C, WIESEN, G E, SCHAIBERGER
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Lipid peroxidation and lipid peroxide detected by chemiluminescence
Free Radical Biology and Medicine, 1987This article emphasizes the advantages of using a luminescence spectrometer based on photon counting techniques for the detection of lipid peroxidation. An overview is presented of how chemiluminescence can be stimulated in the luminol-cytochrome c heme peptide system as an assay for lipid hydroperoxides.
T, Iwaoka, F, Tabata, T, Takahashi
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Hydrogen peroxide and hematin in microsomal lipid peroxidation
Journal of Inorganic Biochemistry, 1981Lipids of rat liver microsomes underwent peroxidation with production of malondialdehyde in the presence of H2O2 and hematin. Rates of peroxidation of 27-33 nmol of MDA formed/mg of microsomal protein/30 min were measured with 5 mM H2O2 and 10 microM hematin at 22 degrees C. Histidine (0.01 M) caused a 55% inhibition.
URSINI, FULVIO +4 more
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The Lancet, 1988
Free-radical-mediated lipid peroxidation has become closely associated with destructive biochemical processes and, more recently, with disease. Its potential survival value may be overlooked.
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Free-radical-mediated lipid peroxidation has become closely associated with destructive biochemical processes and, more recently, with disease. Its potential survival value may be overlooked.
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Organic Peroxides, Hydrogen Peroxide, Epoxides, and Neoplasia
Radiation Research Supplement, 1963Preliminary data are reported that support the suspicion that organic peroxides may possess carcinogenic properties. This suspicion in large measure relates to the acknowledged mutagenicity of certain peroxides. As a possible mechanism of action it is suggested that peroxides may act by catalyzing the depolymerization of deoxyribonucleic (DNA) and ...
P, KOTIN, H L, FALK
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Hematin- and peroxide-catalyzed peroxidation of phospholipid liposomes
Archives of Biochemistry and Biophysics, 1991The effect of hydroperoxides on hematin-catalyzed initiation and propagation of lipid peroxidation was examined utilizing soybean phosphatidylcholine liposomes as model membranes. Polarographic and spectrophotometric methods revealed a bimodal pseudocatalytic activity for hematin.
E H, Kim, A, Sevanian
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Protective mechanisms against peptide and protein peroxides generated by singlet oxygen
Free Radical Biology and Medicine, 2004 Reaction of certain amino acids, peptides, and proteins with singlet oxygen yields substrate-derived peroxides. Recent studies have shown that these species are formed within intact cells and can inactivate key cellular enzymes.
Philip E Morgan +2 more
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Coulometric microdetermination of peroxides—II☆Organic peroxides
Talanta, 1973An iodometric method for the rapid microdetermination of organic peroxides, utilizing electrochemical reduction in the iodine-iodide system, has been developed. After complete reaction between peroxide and iodide in an acidic semi-aqueous medium the iodine produced is reduced at a rotating platinum electrode, at constant potential.
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Coulometric microdetermination of peroxides—I. Hydrogen peroxide
Talanta, 1973An electroanalytical method, based on controlled-potential coulometry in the iodine-iodide system, has been developed for determination of small amounts of hydrogen peroxide. The sample is added to an electrolyte containing an acid solution of iodide and the iodine, which is produced rapidly, is reduced at a rotating platinum electrode.
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