Results 151 to 160 of about 19,535 (281)
Peroxiredoxins are a family of antioxidant enzymes conserved from bacteria to humans. In Saccharomyces cerevisiae, there exist five peroxiredoxins, among which Tsa2p shares striking homology with the well described Tsa1p but has not been extensively ...
Wong, CM +4 more
core +1 more source
This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao +6 more
wiley +1 more source
The role of peroxiredoxins in the regulation of pro-survival mechanisms in human spermatozoa
Infertility affects 1 in 6 couples both in Canada and worldwide and in around half of these cases, male factors are to blame. Male factor infertility has been associated with oxidative stress, which can be caused either by an increase in the production ...
Yu, Alex
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Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu +9 more
wiley +1 more source
Oxidative stress induced by MPTP promotes hnRNP A1/A2–dependent alternative splicing toward PKM2 in dopaminergic neurons. Elevated PKM2 transactivates Nrf2, enhances antioxidant gene expression, and protects neurons from oxidative damage and degeneration.
Meng Mei +6 more
wiley +1 more source
Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie +5 more
wiley +1 more source
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja +3 more
wiley +1 more source
The bioactive composition, antioxidant capacity, and glycemic‐regulating properties of Basella alba L. leaf, fruit, and stem were comparatively analyzed using gas chromatography–mass spectrometry (GC–MS), Fourier‐transform infrared spectroscopy (FTIR), in vitro assays, and molecular docking analyses.
Shorna Das +4 more
wiley +1 more source
Detoxification of peroxides in the chloroplast: What's the role of 2-Cys peroxiredoxins
Baier M, König J, Horling F, Dietz K-J. Detoxification of peroxides in the chloroplast: What's the role of 2-Cys peroxiredoxins. In: Proceedings of the International Congress on Photosynthesis.
Dietz, Karl-Josef +3 more
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Li WX, Lamkemeyer P, Finkemeier I, Baier M, Kandlbinder A, Dietz K-J. PLANT PEROXIREDOXINS: DETOXIFICATION OF PEROXIDES AND REDOX SENSING IN CONTEXT OF METABOLISM AND DEVELOPMENT. ACTA PHYSIOLOGIAE PLANTARUM.
Finkemeier, I +5 more
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