Results 231 to 240 of about 261,210 (338)

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

International Journal of Cancer, EarlyView.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source

Aerobic Exercise Modulates Lipo-Toxicity Genes Expression in Cardiac Tissue of Obese Rats Induced with High-Fat and Fructose Diet. [PDF]

Adv Biomed Res
Khadem F, Shariati M, Kavehzadeh H, Cheraghian A, Salemi A.   +4 more
europepmc   +1 more source

Peroxisome Metabolism Pathway and EHHADH Expression are Downregulated in Macrophages in Neutrophilic Asthma

Gongqi Chen, Wei Gu, Chunli Huang, Weiqiang Kong, Lu Zhao, Huiru Jie, Guohua Zhen   +6 more
openalex   +1 more source

Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells

International Journal of Cancer, EarlyView.
What's New? Exercise releases bioactive molecules into the bloodstream that can directly slow cancer cell growth. In colon cancer, this may help limit disease progression. Here, using colon cancer cells, the authors investigated the effects of exercise‐conditioned human serum on DNA repair mechanisms. Notably, acute exercise in humans elicited systemic
Samuel T. Orange, Emily Dodd, Sharanya Nath, Hannah Bowden, Alastair R. Jordan, Hannah Tweddle, Ann Hedley, Ifeoma Chukwuma, Ian Hickson, Sweta Sharma Saha   +9 more
wiley   +1 more source

Protein Kinase C promotes peroxisome biogenesis and peroxisome-endoplasmic reticulum interaction. [PDF]

J Cell Biol
Borisyuk A, Howman C, Pattabiraman S, Kaganovich D, Amen T.   +4 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Alterations in peroxisome-mitochondria interplay in skeletal muscle accelerate muscle dysfunction. [PDF]

Nat Commun
Scalabrin M, Turco E, Davigo I, Filadi R, Nogara L, Gherardi G, Barazzuol L, Armani A, Trani G, Negro S, Franco-Romero A, Jaspers Y, Baschiera E, De Cegli R, Del Prete E, Cali T, Blaauw B, Salviati L, Rigoni M, Mammucari C, Caspar-Bauguil S, Moro C, Pizzo P, Sandri M, Kemp S, Romanello V.   +25 more
europepmc   +1 more source

Consecutive Steps of Nucleoside Triphosphate Hydrolysis Are Driving Transport of Precursor Proteins into the Endoplasmic Reticulum [PDF]

, 1992
Klappa, Peter, Lill, Roland, Müller, Günter, Neupert, Walter, Schlenstedt, Gabriel, Wiech, Hans, Zimmermann, Richard   +6 more
core   +1 more source

Psammaplin A and Its Analogs Attenuate Oxidative Stress in Neuronal Cells through Peroxisome Proliferator-Activated Receptor γ Activation [PDF]

Rebeca Alvariño, Amparo Alfonso, Jioji N. Tabudravu, Jesús M. González-Jartı́n, Khalid S. Al Maqbali, Marwa Elhariry, Mercedes R. Vieytes, Luís M. Botana   +7 more
openalex   +1 more source

Inflammatory bowel disease and metabolic reprogramming: From pathological mechanisms to targeted interventions

Interdisciplinary Medicine, EarlyView.
This review explores the role of metabolic reprogramming in inflammatory bowel disease (IBD) by focusing on immune and epithelial cell metabolism, microbial metabolites, and their impact on inflammation. It discusses emerging metabolic therapies and emphasizes the importance of personalized microbiota‐targeted approaches to improve clinical outcomes in
Zemin Tian, Yinde Huang, Ying Wang, Chenyu Zhao, Zhaokai Zhou, Hua Yang, Yuan Qiu   +6 more
wiley   +1 more source