Results 241 to 250 of about 188,367 (306)

Targeting the PPAR-γ-ABC transporter axis ameliorates secondary pulmonary alveolar proteinosis induced by indium oxide nanoparticles. [PDF]

Part Fibre Toxicol
Jeon S, Kim G, Cho WS.
europepmc   +1 more source

The Microbiome as a Mirror: Distinguishing Healthy Individuals From Chronic Constipated Patients and Identifying Those With Hidden Psychiatric Burden

Microbiota Medicine Research, EarlyView.
Gut microbiota signatures distinguish chronic constipated patients from healthy individuals, supporting noninvasive diagnostic potential. Despite challenges in identifying psychiatric‐related comorbidities, microbial alterations, particularly in neurotransmitter and inflammatory pathways, lay the groundwork for future companion diagnostics and ...
Hongyan Qi, Ting Yu, Weichen Liu, Ya Jiang, Die Chen, Li Gao, Hui Li, Yurong Tang   +7 more
wiley   +1 more source

Lipid ciliology: specialized ciliary membrane lipids in physiology and disease. [PDF]

Front Cell Dev Biol
Hasan A, Morita T, Hirosawa M, Kitamura N, Murakami R, Mikuni M, Kobayashi D, Itabashi T, Miyamoto T.   +8 more
europepmc   +1 more source

The role of tryptophan hydroxylase‐1 in metabolic dysfunction‐associated steatotic liver disease

Pediatric Investigation, EarlyView.
Silencing hepatic tryptophan hydroxylase 1 (TPH1) alleviated diet‐induced steatotic liver disease by reducing lipid accumulation, oxidative stress, inflammation, fibrosis, and hepatocyte apoptosis. These protective effects were mediated, at least in part, through restoration of Parkin‐dependent mitochondrial autophagy, identifying hepatic TPH1 as a ...
Shuangzhen Jia, Xiaolin Ye, Zhaoxia Wang, Jie Wu   +3 more
wiley   +1 more source

Integrative Multi-omics and Machine Learning Reveal the Therapeutic Mechanisms of Juanyu-Xiaozhi Formula in Metabolic Dysfunction-associated Steatotic Liver Disease and Hepatic Fibrosis via the AP-1/PPARγ/SCD1 Axis. [PDF]

J Clin Transl Hepatol
Jin Z, Huang Y, Zeng C, Zhang Y, Qiu Y, Yang Y, Liu H.   +6 more
europepmc   +1 more source

Peroxisomal Lipid Metabolism as a Therapeutic Target in Leukemia. [PDF]

Mol Nutr Food Res
Parfenova EN, Spagnuolo PA.
europepmc   +1 more source

Metabolic signatures and machine learning identify gut-liver-heart axis dysfunction as a potential link to major adverse cardiovascular events in coronary artery disease. [PDF]

Cardiovasc Diabetol Endocrinol Rep
Lin MQ, Wong CK, Au KW, Cheung CY, Lau YM, Liao SY, Lam KS, Xu A, Tse HF.   +8 more
europepmc   +1 more source

Spatial Engineering of Yarrowia lipolytica for the Biosynthesis of Capsanthin. [PDF]

Biotechnol J
Zhang J, Sun L, Zhang L, Din C, Gu Z, Chen L, Xu S.   +6 more
europepmc   +1 more source

Organelle Crosstalk and Metabolic Reprogramming in Idiopathic Pulmonary Fibrosis: Mechanisms and Therapeutic Implications. [PDF]

Cell Biochem Funct
Zhang Y, Teng L, Gong L, Fu Y, Qian M.
europepmc   +1 more source

From metabolic dysregulation to malignancy: the presence of <i>ZPR1</i> in gastrointestinal and hepatopancreatobiliary malignancies. [PDF]

J Gastrointest Oncol
Chittilla M, Nagdev P.
europepmc   +1 more source