Results 281 to 290 of about 261,210 (338)

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Restoring metabolic flexibility: targeting organelle interaction networks in the pathogenesis and therapy of MASLD. [PDF]

open access: yesFront Cell Dev Biol
Liu Y   +9 more
europepmc   +1 more source

Sodium butyrate ameliorates renal tubular lipid accumulation through a protein phosphatase 2A/transcription factor EB axis in diabetic nephropathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Extensive evidence indicates that lipid accumulation causes renal tubular injury, which further contributes to diabetic nephropathy (DN) progression. Short‐chain fatty acids (SCFAs) play an important role in the maintenance of cellular metabolic health.
Jiayin Tao   +12 more
wiley   +1 more source

Production of triacetic acid lactone from oleic acid by engineering the yeast Candida viswanathii. [PDF]

open access: yesMicrob Cell Fact
Ghosh S   +8 more
europepmc   +1 more source

Prioritising research on endocrine disruption in the marine environment: a global perspective

open access: yesBiological Reviews, EarlyView.
ABSTRACT A healthy ocean is a crucial life support system that regulates the global climate, is a source of oxygen and supports major economic activities. A vast and understudied biodiversity from micro‐ to macro‐organisms is integral to ocean health.
Patricia I. S. Pinto   +23 more
wiley   +1 more source

Ninjin’yoeito Ameliorates Skeletal Muscle Complications in COPD Model Mice by Upregulating Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Expression

open access: green, 2020
Atsushi Miyamoto   +10 more
openalex   +1 more source

Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients

open access: yesClinical &Experimental Allergy, EarlyView.
Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna   +10 more
wiley   +1 more source

Peroxisomal Alterations in Prostate Cancer: Metabolic Shifts and Clinical Relevance. [PDF]

open access: yesCancers (Basel)
Hussein MAF   +5 more
europepmc   +1 more source

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