Results 41 to 50 of about 261,210 (338)
Frontiers in Cell and Developmental Biology, 2022 Mast cells are specialized, tissue resident, immune effector cells able to respond to a wide range of stimuli. MCs are involved in the regulation of a variety of physiological functions, including vasodilation, angiogenesis and pathogen elimination.
Dihia Meghnem +10 more
doaj +1 more source
Virulence, 2020 Enterovirus 71 (EV71) infection causes hand, foot, and mouth disease (HFMD), and even fatal neurological complications. However, the mechanisms underlying EV71 neurological pathogeneses are largely unknown.
Lei You +10 more
doaj +1 more source
Transcriptional Regulator TonEBP Mediates Oxidative Damages in Ischemic Kidney Injury [PDF]
, 2019 TonEBP (tonicity-responsive enhancer binding protein) is a transcriptional regulator whose expression is elevated in response to various forms of stress including hyperglycemia, inflammation, and hypoxia.
Choi, Soo Youn +10 more
core +1 more source
Reprogramming Hansenula polymorpha for penicillin production: expression of the Penicillium chrysogenum pcl gene [PDF]
, 2007 We aim to introduce the penicillin biosynthetic pathway into the methylotrophic yeast Hansenula polymorpha. To allow simultaneous expression of the multiple genes of the penicillin biosynthetic pathway, additional markers were required.
Gidijala, Loknath, +3 more
core +2 more sources
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Transcriptional responses to fatty acid are coordinated by combinatorial control
Molecular Systems Biology, 2007 In transcriptional regulatory networks, the coincident binding of a combination of factors to regulate a gene implies the existence of complex mechanisms to control both the gene expression profile and specificity of the response.
Jennifer J Smith +7 more
doaj +1 more source
Membrane Processing and Steady-State Regulation of the Alternative Peroxisomal Import Receptor Pex9p
Frontiers in Cell and Developmental Biology, 2020 Import of peroxisomal matrix proteins with a type 1 peroxisomal targeting signal (PTS1) in Saccharomyces cerevisiae is facilitated by cytosolic import receptors Pex5p and Pex9p. While Pex5p has a broad specificity for all PTS1 proteins independent of the
Markus Rudowitz +2 more
doaj +1 more source
Spatiotemporal Dynamic Regulation of Organelles During Meiotic Development, Insights From Fungi
Frontiers in Cell and Developmental Biology, 2022 Eukaryotic cell development involves precise regulation of organelle activity and dynamics, which adapt the cell architecture and metabolism to the changing developmental requirements. Research in various fungal model organisms has disclosed that meiotic
Fernando Hernández-Sánchez +1 more
doaj +1 more source
PPARα contributes to protection against metabolic and inflammatory derangements associated with acute kidney injury in experimental sepsis [PDF]
, 2019 Sepsis‐associated acute kidney injury (AKI) is a significant problem in critically ill children and adults resulting in increased morbidity and mortality. Fundamental mechanisms contributing to sepsis‐associated AKI are poorly understood.
Bennion, Brock G +10 more
core +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source