Results 21 to 30 of about 153,107 (266)

Delineating transitions during the evolution of specialised peroxisomes: Glycosome formation in kinetoplastid and diplonemid protists

open access: yesFrontiers in Cell and Developmental Biology, 2022
One peculiarity of protists belonging to classes Kinetoplastea and Diplonemea within the phylum Euglenozoa is compartmentalisation of most glycolytic enzymes within peroxisomes that are hence called glycosomes.
Diego Andrade-Alviárez   +6 more
doaj   +1 more source

Cytoprotective Activities of Milk Thistle Seed Oil Used in Traditional Tunisian Medicine on 7-Ketocholesterol and 24S-Hydroxycholesterol-Induced Toxicity on 158N Murine Oligodendrocytes

open access: yesAntioxidants, 2018
The Asteraceae family is economically very important, because many of these plants are grown mainly for their food value, such as lettuce (Lactuca), chicory (Cichorium), and sunflower (Heliantus aminus).
Wiem Meddeb   +8 more
doaj   +1 more source

Neurophysiological, behavioral and morphological abnormalities in the Fabry knockout mice

open access: yesNeurobiology of Disease, 2009
Fabry disease (OMIM 301500) is a rare X-linked recessive disorder caused by mutations in the α-galactosidase gene (GLA). Loss of α-galactosidase (α-Gal) activity leads to the abnormal accumulation of glycosphingolipids in lysosomes predominantly of ...
L.G. Rodrigues   +7 more
doaj   +1 more source

Exercise, Nutrition, and Supplements in the Muscle Carnitine Palmitoyl-Transferase II Deficiency: New Theoretical Bases for Potential Applications

open access: yesFrontiers in Physiology, 2021
Carnitine palmitoyltransferase II (CPTII) deficiency is the most frequent inherited disorder regarding muscle fatty acid metabolism, resulting in a reduced mitochondrial long-chain fatty acid oxidation during endurance exercise. This condition leads to a
Massimo Negro   +9 more
doaj   +1 more source

No peroxisome is an island — Peroxisome contact sites

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2016
In order to optimize their multiple cellular functions, peroxisomes must collaborate and communicate with the surrounding organelles. A common way of communication between organelles is through physical membrane contact sites where membranes of two organelles are tethered, facilitating exchange of small molecules and intracellular signaling.
Shai, Nadav   +2 more
openaire   +2 more sources

ISOC1 Modulates Inflammatory Responses in Macrophages through the AKT1/PEX11B/Peroxisome Pathway

open access: yesMolecules, 2022
Inflammation underlies a variety of physiological and pathological processes and plays an essential role in shaping the ensuing adaptive immune responses and in the control of pathogens.
Xiaoyuan Lin   +6 more
doaj   +1 more source

Characterization of the Peroxisomal Proteome and Redox Balance in Human Prostate Cancer Cell Lines

open access: yesAntioxidants
Prostate cancer (PCa) is associated with disruptions in cellular redox balance. Given the intricate role of peroxisomes in redox metabolism, we conducted comprehensive proteomics analyses to compare peroxisomal and redox protein profiles between benign ...
Mohamed A. F. Hussein   +5 more
doaj   +1 more source

Cytoprotective and Antioxidants in Peroxisomal Neurodegenerative Diseases

open access: yesProceedings, 2019
Several of the peroxisomal neurodegenerative disorders are the consequence of a specific deficiency of an enzyme or a transporter involved in peroxisomal beta-oxidation of very long chain fatty acids [1,2].
Mustapha Cherkaoui-Malki   +9 more
doaj   +1 more source

Peroxisomes Regulate Cellular Free Fatty Acids to Modulate Mast Cell TLR2, TLR4, and IgE-Mediated Activation

open access: yesFrontiers in Cell and Developmental Biology, 2022
Mast cells are specialized, tissue resident, immune effector cells able to respond to a wide range of stimuli. MCs are involved in the regulation of a variety of physiological functions, including vasodilation, angiogenesis and pathogen elimination.
Dihia Meghnem   +10 more
doaj   +1 more source

Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation

open access: yesVirulence, 2020
Enterovirus 71 (EV71) infection causes hand, foot, and mouth disease (HFMD), and even fatal neurological complications. However, the mechanisms underlying EV71 neurological pathogeneses are largely unknown.
Lei You   +10 more
doaj   +1 more source

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