Results 21 to 30 of about 246,925 (304)

Cytotoxic and Antioxidant Activities of Imine Analogs of Trans-Resveratrol towards Murine Neuronal N2a Cells

Molecules, 2022
Trans-resveratrol is a natural polyphenol showing numerous biological properties, especially anti-tumoral and antioxidant activity. Among numerous resveratrol derivatives, aza-stilbenes, which bear an imine bound, show interesting biological activities ...
Mohamed Ksila, Anne Vejux, Emmanuelle Prost-Camus, Philippe Durand, Imen Ghzaiel, Thomas Nury, Dorian Duprey, Smail Meziane, Olfa Masmoudi-Kouki, Norbert Latruffe, Taoufik Ghrairi, Michel Prost, Gérard Lizard, Dominique Vervandier-Fasseur   +13 more
doaj   +1 more source

Cadmium and arsenic-induced-stress differentially modulates Arabidopsis root architecture, peroxisome distribution, enzymatic activities and their nitric oxide content [PDF]

, 2020
In plant cells, cadmium (Cd) and arsenic (As) exert toxicity mainly by inducing oxidative stress through an imbalance between the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS), and their detoxification. Nitric oxide (NO)
Altamura, M. M., Corpas, F. J., D'Angeli, S., Falasca, G., Piacentini, D.   +4 more
core   +2 more sources

A Pex7 Deficient Mouse Series Correlates Biochemical and Neurobehavioral Markers to Genotype Severity—Implications for the Disease Spectrum of Rhizomelic Chondrodysplasia Punctata Type 1

Frontiers in Cell and Developmental Biology, 2022
Rhizomelic chondrodysplasia punctata type 1 (RCDP1) is a peroxisome biogenesis disorder caused by defects in PEX7 leading to impairment in plasmalogen (Pls) biosynthesis and phytanic acid (PA) oxidation.
Wedad Fallatah, Wedad Fallatah, Wei Cui, Erminia Di Pietro, Grace T. Carter, Brittany Pounder, Fabian Dorninger, Christian Pifl, Ann B. Moser, Johannes Berger, Nancy E. Braverman, Nancy E. Braverman   +11 more
doaj   +1 more source

Metabolic interactions between vitamin A and conjugated linoleic acid [PDF]

, 2014
Lipid-soluble molecules share several aspects of their physiology due to their common adaptations to a hydrophilic environment, and may interact to regulate their action in a tissue-specific manner.
BANNI, SEBASTIANO, Belury, MA, CARTA, GIANFRANCA, Cordeddu, L, Giordano, E, MURRU, MARIA ELISABETTA, Ortiz, B, Quadro, L   +7 more
core   +2 more sources

Induction of Neuronal Differentiation of Murine N2a Cells by Two Polyphenols Present in the Mediterranean Diet Mimicking Neurotrophins Activities: Resveratrol and Apigenin

Diseases, 2018
In the prevention of neurodegeneration associated with aging and neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease), neuronal differentiation is of interest.
Amira Namsi, Thomas Nury, Haithem Hamdouni, Aline Yammine, Anne Vejux, Dominique Vervandier-Fasseur, Norbert Latruffe, Olfa Masmoudi-Kouki, Gérard Lizard   +8 more
doaj   +1 more source

Aza- and Azo-Stilbenes: Bio-Isosteric Analogs of Resveratrol

Molecules, 2020
Several series of natural polyphenols are described for their biological and therapeutic potential. Natural stilbenoid polyphenols, such as trans-resveratrol, pterostilbene and piceatannol are well-known for their numerous biological activities. However,
Gérard Lizard, Norbert Latruffe, Dominique Vervandier-Fasseur   +2 more
doaj   +1 more source

A Model of Lipid Monolayer–Bilayer Fusion of Lipid Droplets and Peroxisomes

Membranes, 2022
Lipid droplets are unique organelles that store neutral lipids encapsulated by the lipid monolayer. In some processes of cellular metabolism, lipid droplets interact with peroxisomes resulting in the fusion of their envelopes and the formation of ...
Maksim A. Kalutsky, Timur R. Galimzyanov, Rodion J. Molotkovsky   +2 more
doaj   +1 more source

A comparative study of peroxisomal structures in Hansenula polymorpha pex mutants [PDF]

, 2007
In a recent study, we performed a systematic genome analysis for the conservation of genes involved in peroxisome biogenesis (PEX genes) in various fungi.
Klei, Ida J. van der,, Koek, Anne,, Komori, Masayuki,, Veenhuis, Marten,   +3 more
core   +2 more sources

Prevention of 7-Ketocholesterol-Induced Overproduction of Reactive Oxygen Species, Mitochondrial Dysfunction and Cell Death with Major Nutrients (Polyphenols, ω3 and ω9 Unsaturated Fatty Acids) of the Mediterranean Diet on N2a Neuronal Cells

Molecules, 2020
The brain, which is a cholesterol-rich organ, can be subject to oxidative stress in a variety of pathophysiological conditions, age-related diseases and some rare pathologies.
Aline Yammine, Thomas Nury, Anne Vejux, Norbert Latruffe, Dominique Vervandier-Fasseur, Mohammad Samadi, Hélène Greige-Gerges, Lizette Auezova, Gérard Lizard   +8 more
doaj   +1 more source

Edgetic Perturbations Contribute to Phenotypic Variability in PEX26 Deficiency

Frontiers in Genetics, 2021
Peroxisomes share metabolic pathways with other organelles and peroxisomes are embedded into key cellular processes. However, the specific function of many peroxisomal proteins remains unclear and restricted knowledge of the peroxisomal protein ...
Amelie S. Lotz-Havla, Mathias Woidy, Philipp Guder, Jessica Schmiesing, Ralf Erdmann, Hans R. Waterham, Ania C. Muntau, Søren W. Gersting   +7 more
doaj   +1 more source