Results 241 to 250 of about 91,703 (262)

Hepatic regeneration in peroxisome proliferator-activated receptor α-null mice after partial hepatectomy

Hepatology Research, 2002
Peroxisome proliferator activated receptor alpha (PPARalpha), a member of the nuclear hormone receptor superfamily, is essential for hepatic pleiotropic effects induced by peroxisome proliferators including cell proliferation. In a previous study, we have shown that PPARalpha null mice do not show increased hepatocyte proliferation after administration
M Sambasiva, Rao, Jeffrey M., Peters, Frank J., Gonzalez, Janardan K., Reddy   +3 more
openaire   +2 more sources

Retinoic acid activation of peroxisome proliferation-activated receptor δ represses obesity and insulin resistance

Nutrition Reviews, 2010
Retinoic acid (RA) was found to be a ligand for peroxisome proliferation-activated receptor delta (PPARdelta) as well as the classical RA receptor (RAR). Carrier proteins that move the RA from the cytosol into the nucleus are the fatty acid-binding protein 5 (FABP5), activating PPARdelta, and the cellular retinoic acid-binding protein II (CRABPII ...
openaire   +2 more sources

027 Protective role of peroxisome proliferator-activated receptor Î/Î′ in cardiac dysfunction and organ injury/inflammation caused by endotoxin in mice

Heart, 2010
Peroxisome proliferator-activated receptor (PPAR)-I2/I′ is a transcription factor that belongs to the PPAR nuclear hormone receptor family. There is little information about the ligands of PPAR-I2/I′ and the effect of specific activation (eg, GW0742) of PPAR-I2/I′ in animal models of shock. Here we used …
openaire   +1 more source

Peroxisome Proliferator Activated Receptor-α Expression in Human Liver

Molecular Pharmacology, 1998
The peroxisome proliferator activated receptor α (PPAR) is a member of the steroid/hormone receptor superfamily that mediates the peroxisome proliferator-dependent transcriptional activation of genes encoding several peroxisomal and microsomal enzymes as
Colin N A Palmer, Keith J Griffin, Judy L Raucy   +2 more
exaly   +2 more sources

Antiinflammatory Roles of Peroxisome Proliferator–activated Receptor γ in Human Alveolar Macrophages

American Journal of Respiratory and Critical Care Medicine, 2004
Shigekazu Sasaki, Takafumi Suda
exaly  

Agonists of Peroxisome Proliferator-Activated Receptor γ Inhibit Cell Growth in Malignant Melanoma

Journal of Investigative Dermatology, 2002
Rotraut Mössner, Ullrich Kruger, Christine Neumann   +2 more
exaly  

Intimal Smooth Muscle Cells as a Target for Peroxisome Proliferator-Activated Receptor-γ Ligand Therapy

Circulation Research, 2002
David Bishop-Bailey, Timothy Hla, Timothy D Warner   +2 more
exaly  

Decreased Longevity and Enhancement of Age-Dependent Lesions in Mice Lacking the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα)

Toxicologic Pathology, 2004
Russell C Cattley, J Christopher Corton
exaly  

Roles of Peroxisome Proliferator–Activated Receptor–α and –γ in the Development of Non–Small Cell Lung Cancer

American Journal of Respiratory Cell and Molecular Biology, 2010
Michael K Y Hsin, George G Chen
exaly  

Cardiomyocyte-Specific Knockout and Agonist of Peroxisome Proliferator–Activated Receptor-γ Both Induce Cardiac Hypertrophy in Mice

Circulation Research, 2005
Sheng Zhong Duan, Mark W Russell, David S Milstone   +2 more
exaly