Peroxisome proliferator-activated receptor

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Peroxisome Proliferator Activated Receptors and Cannabinoids

2017
Cannabinoids are a complex group of molecules that comprise phytocannabinoids, endocannabinoids and synthetic cannabinoids. Cannabinoids were initially identified by its ability to bind and activate the classical cannabinoid receptors CB1 and CB2.
Muñoz, E. +3 more
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Drugs targeting peroxisome proliferator-activated receptors

Drug Discovery Today
The year 2024 witnessed the accelerated approvals of two peroxisome proliferator-activated receptor (PPAR) agonists for the treatment of primary biliary cholangitis (PBC). PPARs, including three isoforms (PPARα, PPARγ, and PPARδ), are therapeutic targets generating considerable debate yet also seeing significant advances in their successful targeting ...
Zhouling Xie +3 more
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Peroxisome proliferator activated receptors and obesity

European Journal of Pharmacology, 2002
The peroxisome proliferator activated receptors (PPARs) are a group of ligand-activated transcription factors that govern numerous biological processes, including energy metabolism, cell proliferation, and inflammation. Three different PPAR isotypes can be distinguished: alpha, beta and gamma.
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Receptors | Peroxisome Proliferator-Activated Receptors

2021
Mary C. Sugden +3 more
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The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation