Results 191 to 200 of about 72,675 (217)

Diagnosing and Treating Periodontitis and Multimorbidity Altogether: The Case Example of the Physical Exercise Hormone Irisin

open access: yesJournal of Periodontal Research, EarlyView.
Irisin is an extracellular peptide stimulated by exercise and could act as both a biomarker and mediate the positive impact of exercise. This scoping review synthesizes human evidence on irisin variations in non‐communicable diseases, showing an increase of irisin in saliva and gingival tissues in periodontitis, potentially reflecting reparative or ...
Larysa Saboya Cavalotti Perdonsini   +4 more
wiley   +1 more source

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

open access: yesJournal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw   +4 more
wiley   +1 more source

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

open access: yesObesity Reviews, EarlyView.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye   +6 more
wiley   +1 more source

Hepatic regeneration in peroxisome proliferator-activated receptor α-null mice after partial hepatectomy

Hepatology Research, 2002
Peroxisome proliferator activated receptor alpha (PPARalpha), a member of the nuclear hormone receptor superfamily, is essential for hepatic pleiotropic effects induced by peroxisome proliferators including cell proliferation. In a previous study, we have shown that PPARalpha null mice do not show increased hepatocyte proliferation after administration
M Sambasiva, Rao   +3 more
openaire   +2 more sources

Molecular effects of leptin on peroxisome proliferator activated receptor gamma (PPAR-γ) mRNA expression in rat's adipose and liver tissue

Cellular and Molecular Biology, 2017
Leptin is a 16-kDa peptide hormone secreted by adipose tissue that participates in the regulation of energy homeostasis. The aim of this study was to determine the effect of leptin injection on mRNA expression of peroxisome proliferator-activated receptor gamma (PPAR-γ) and comparison of PPAR-γ mRNA expression in rat's adipose and liver tissue ...
A, Abbasi   +5 more
openaire   +2 more sources

027 Protective role of peroxisome proliferator-activated receptor Î/Î′ in cardiac dysfunction and organ injury/inflammation caused by endotoxin in mice

Heart, 2010
Peroxisome proliferator-activated receptor (PPAR)-I2/I′ is a transcription factor that belongs to the PPAR nuclear hormone receptor family. There is little information about the ligands of PPAR-I2/I′ and the effect of specific activation (eg, GW0742) of PPAR-I2/I′ in animal models of shock. Here we used …
openaire   +1 more source

Retinoic acid activation of peroxisome proliferation-activated receptor δ represses obesity and insulin resistance

Nutrition Reviews, 2010
Retinoic acid (RA) was found to be a ligand for peroxisome proliferation-activated receptor delta (PPARdelta) as well as the classical RA receptor (RAR). Carrier proteins that move the RA from the cytosol into the nucleus are the fatty acid-binding protein 5 (FABP5), activating PPARdelta, and the cellular retinoic acid-binding protein II (CRABPII ...
openaire   +2 more sources

Antiinflammatory Roles of Peroxisome Proliferator–activated Receptor γ in Human Alveolar Macrophages

American Journal of Respiratory and Critical Care Medicine, 2004
Shigekazu Sasaki, Takafumi Suda
exaly  

Agonists of Peroxisome Proliferator-Activated Receptor γ Inhibit Cell Growth in Malignant Melanoma

Journal of Investigative Dermatology, 2002
Rotraut Mössner   +2 more
exaly  

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