Results 141 to 150 of about 103,678 (289)

A Comprehensive Review on Nutrition, Phytochemistry, Pharmacology and Food Application Perspectives of Bioactive Rich Superfruits

Future Postharvest and Food, EarlyView.
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja, Javid Iqbal Mir, Mahendra Kumar Verma, Aamir Hussain Dar   +3 more
wiley   +1 more source

Urolithin A, a Diet‐Derived Gut Microbial Metabolite Against Pulmonary Hypertension Identified via Molecular Docking, Molecular Dynamics and Surface Plasmon Resonance

Food Safety and Health, EarlyView.
Urolithin A, a gut microbial metabolite, binds TNF to suppress proliferation, inflammation, and oxidative stress, offering a promising microbe‐derived therapeutic avenue for pulmonary hypertension. ABSTRACT Pulmonary hypertension (PH) is a complex and multifactorial disease that poses a significant clinical challenge.
Yujie Qu, Yinghua Huo, Yichen Wang, Yao Mu, Xue Yu, Leiyu Tian, Jian Guo, Xuezhi Yang, Yucai Chen   +8 more
wiley   +1 more source

Osteoarthritis: Role of Peroxisome Proliferator-Activated Receptors. [PDF]

Int J Mol Sci, 2023
Sheng W, Wang Q, Qin H, Cao S, Wei Y, Weng J, Yu F, Zeng H.   +7 more
europepmc   +1 more source

An Overview of the Role of Peroxisome Proliferator-activated Receptors in Liver Diseases. [PDF]

J Clin Transl Hepatol, 2023
Changizi Z, Kajbaf F, Moslehi A.
europepmc   +1 more source

اثر محرک‌های گیرنده‌ی فعال کننده‌ی پرولیفراسیون پروکسی‌زوم (PPARها) بر بازسازی قلبی (Cardiac remodeling) در رت‌های سالم و مبتلا به دیابت

مجله دانشکده پزشکی اصفهان, 2014
مقدمه: گیرنده‌های فعال کننده‌ی تکثیر پروکسی‌زوم‌ها (PPARs یا Peroxisome proliferator–activated receptors) گروهی از گیرنده‌های هسته‌ای وابسته به لیگاند می‌باشند كه به عنوان عوامل نسخه‌برداری عمل می‌کنند و در انسان دارای 3 ایزوفرم شناخته شده‌ی β/δ، γ و α ...
Ensieh Salehi, Majid Khazaei, Bahman Rashidi   +2 more
doaj  

The Role of Peroxisome Proliferator-Activated Receptors in Endometrial Cancer. [PDF]

Int J Mol Sci, 2023
Psilopatis I, Vrettou K, Troungos C, Theocharis S.   +3 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

The Role of Peroxisome Proliferator-Activated Receptors in Polycystic Ovary Syndrome. [PDF]

J Clin Med, 2023
Psilopatis I, Vrettou K, Nousiopoulou E, Palamaris K, Theocharis S.   +4 more
europepmc   +1 more source

Synthesized flavone attenuates diabetes‐induced neurodegeneration through regulation of oxidative stress and metabolic‐neurodegenerative molecular pathways

Ibrain, EarlyView.
Neuroprotective efficacy of flavone (2‐phenyl‐4H‐chromen‐4‐one). The study aimed to explore the potential of a synthetic derivative (flavone) of a phytocompound, which is involved in neuroprotection activities. Experimental strategies included the characteristics of compound, in‐silico analysis, and in vivo assessments.
Karishma Sen, Anita Sakarwal, Heera Ram, Suman K. Saha, Nirmal K. Rana, Dharmveer Yadav, Sunil Dutt Shukla, Mukesh Kumar Yadav, Balachandar Vellingiri, Vikas Kumar   +9 more
wiley   +1 more source

Antibiotic Remodeling of the Gut Microbiota Impairs Host Resistance to Secondary Infection

iMetaMed, EarlyView.
Gut microbial dynamics induced by four antibiotics, revealed distinct taxonomic and functional shifts. Vancomycin‐perturbed bacteriomes were proven to promote pathogen resistance to antibiotic treatment. Metronidazole‐treated mice showed pronounced Salmonella translocation to hepatic tissue, and altered Enterococcus avium populations modulated host ...
Miaoyu Li, Ying Chen, Xi Chen, Weili Lu, Jie Liao, Jiaqi Wang, Qiwei Liu, Yanzi Chang, Zeping Xu, Yanye Tu, Yang Zhou, Jing Xue, Binbin Wang, Kang Chen, Keyun Cheng, Chunlai Zeng, Hong Li, Qing Shen   +17 more
wiley   +1 more source