Results 151 to 160 of about 1,310,860 (245)

Pharmacological Targeting of Peroxisome 
Proliferator-activated Receptors for Prevention 
of Radiation-induced Cognitive Decline. [PDF]

Ann Neurosci
Ghanekar S, Raj JAT, Thiruselvan GK, Kulkarni R, Soni M, Chatterjee A, Patro I, Goda JS.   +7 more
europepmc   +1 more source

The Role of Peroxisome Proliferator-Activated Receptors in Polycystic Ovary Syndrome. [PDF]

J Clin Med, 2023
Psilopatis I, Vrettou K, Nousiopoulou E, Palamaris K, Theocharis S.   +4 more
europepmc   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Review Article: Targeting Peroxisome Proliferator-Activated Receptors in Primary Biliary Cholangitis. [PDF]

Aliment Pharmacol Ther
Schattenberg JM, Banales JM, Hirschfield G, Trivedi P, Cable EE, McWherter CA, Billin AN, Crittenden DB, Budas G.   +8 more
europepmc   +1 more source

Comparing Transcriptomic Responses to Chemicals Across Six Species Using the EcoToxChip RNASeq Database

Environmental Toxicology and Chemistry, EarlyView.
Abstract The EcoToxChip project includes RNA‐sequencing data from experiments involving model (Japanese quail, fathead minnow, African clawed frog) and ecological (double‐crested cormorant, rainbow trout, northern leopard frog) species at multiple life stages (whole embryo and adult) exposed to eight chemicals of environmental concern known to perturb ...
Krittika Mittal, Jessica Ewald, Doug Crump, Jessica Head, Markus Hecker, Natacha Hogan, Jianguo Xia, Niladri Basu   +7 more
wiley   +1 more source

Autoinhibition of untimely DNA binding by structural disorder in the full-length peroxisome proliferator-activated receptors (PPARs). [PDF]

Nat Commun
Lalic MR, Thomsen EGK, Thomasen FE, Udupa A, Salehian Andersen E, Kuppermann S, Christensen CG, Holm-Olesen E, Saar D, Prestel A, Bauer LW, McKenna J, Olsen JG, Mandrup S, Hartmann-Petersen R, Jeffries CM, Staller MV, Lindorff-Larsen K, Kragelund BB.   +18 more
europepmc   +1 more source

Peptide Helix-Y¹² as Potential Effector for Peroxisome Proliferator-Activated Receptors. [PDF]

PPAR Res, 2023
Carrillo-Tripp M, Reyes Y, Delgado-Coello B, Mas-Oliva J, Gutiérrez-Vidal R.   +4 more
europepmc   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Visualization and Cluster Analysis of Peroxisome Proliferator-Activated Receptors in Colorectal Cancer: Research Trends and Future Directions. [PDF]

Hum Mutat
Dong B, Zhou B, Zhang H, Wang T, Xu Z, Zhu L, Li Q, Niu B, Sun X.   +8 more
europepmc   +1 more source

Valorization of Citrus Waste for Recovery of Nutritional and Bioactive Compounds: A Comprehensive Review

Future Postharvest and Food, EarlyView.
The various citrus wastes, including the citrus fruit peels, pulp remaining after extraction of juice, and seeds, are the sources of bioactive compounds. The waste parts of oranges, lemons, limes, grapefruits, and mandarins contain the bioactive compounds, flavonoids, ascorbic acid, essential oils, and carotenoids.
Monika, Rhythm Kalsi, Jasleen Kaur Bhasin, Rafeeya Shams, Kshirod Kumar Dash   +4 more
wiley   +1 more source