The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT The instability of atherosclerotic plaques, particularly intraplaque hemorrhage (IPH), drives life‐threatening cardiovascular events, a process in which vascular smooth muscle cell (VSMC)‐derived foam cells play a significant role. We aim to identify key biomarkers associated with VSMC‐derived foam cells and IPH by analyzing data from human ...
Ling‐Lin Qian +4 more
wiley +1 more source
It takes two peroxisome proliferator-activated receptors (PPAR-β/δ and PPAR-γ) to tango idiopathic pulmonary fibrosis. [PDF]
Respir ResBoateng E +13 more
europepmc +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Correction to "Sang-qi Granula Reduces Blood Pressure and Myocardial Fibrosis by Suppressing Inflammatory Responses Associated with the Peroxisome Proliferator-Activated Receptors and Nuclear Factor κB Protein in Spontaneously Hypertensive Rats". [PDF]
Evid Based Complement Alternat Medeuropepmc +1 more source
Potential involvement of peroxisome proliferator-activated receptors in the inhibition of mammary lipid synthesis during diet-induced milk fat depression. [PDF]
J Dairy SciHaile A +4 more
europepmc +1 more source
Obesity, EarlyView.ABSTRACT Objective Incretin‐based obesity therapies (IBTs), especially GLP‐1 receptor agonists (GLP‐1 RAs), effectively treat obesity and improve comorbidities. However, their impact on energy metabolism is unclear. A recent case of acute generalized muscle weakness in a patient with mitochondrial myopathy after tirzepatide exposure raises concerns ...
Bryn Falahee +2 more
wiley +1 more source
Obesity, EarlyView.ABSTRACT Objective High‐fat diet represses Ceacam1 transcription via a PPARα‐mediated mechanism to cause insulin resistance before inflammation develops. The current study investigated whether mutating PPRE‐RXRα in Ceacam1 promoter prevents diet‐induced metabolic abnormalities and hepatic fibrosis in male C57BL6/J mice.
Raziyeh Abdolahipour +9 more
wiley +1 more source
The Peroxisome Proliferator-Activated Receptors of Ray-Finned Fish: Unique Structures, Elusive Functions. [PDF]
BiomoleculesBoukouvala E, Krey G.
europepmc +1 more source
The role of tryptophan hydroxylase‐1 in metabolic dysfunction‐associated steatotic liver disease
Pediatric Investigation, EarlyView.Silencing hepatic tryptophan hydroxylase 1 (TPH1) alleviated diet‐induced steatotic liver disease by reducing lipid accumulation, oxidative stress, inflammation, fibrosis, and hepatocyte apoptosis. These protective effects were mediated, at least in part, through restoration of Parkin‐dependent mitochondrial autophagy, identifying hepatic TPH1 as a ...
Shuangzhen Jia +3 more
wiley +1 more source
Serum adiponectin and peroxisome proliferator-activated receptors-γ levels in obese patients with and without prediabetes. [PDF]
Rev Assoc Med Bras (1992)Gul MA +4 more
europepmc +1 more source