Results 151 to 160 of about 42,473 (314)
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Catalase Degradation in Sunflower Cotyledons during Peroxisome Transition from Glyoxysomal to Leaf Peroxisomal Function [PDF]
Rainer Eising, Bernt Gerhardt
openalex +1 more source
Abstract The EcoToxChip project includes RNA‐sequencing data from experiments involving model (Japanese quail, fathead minnow, African clawed frog) and ecological (double‐crested cormorant, rainbow trout, northern leopard frog) species at multiple life stages (whole embryo and adult) exposed to eight chemicals of environmental concern known to perturb ...
Krittika Mittal +7 more
wiley +1 more source
Peroxisomal-dependent signalling and dynamics modulate plant stress responses: reactive oxygen and nitrogen species as key molecules. [PDF]
Molina-Moya E +4 more
europepmc +1 more source
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers +10 more
wiley +1 more source
Peroxisomes as emerging clinical targets in neuroinflammatory diseases. [PDF]
Roczkowsky A +3 more
europepmc +1 more source
Translocation of acyl-CoA oxidase into peroxisomes requires ATP hydrolysis but not a membrane potential. [PDF]
Tsuneo Imanaka +2 more
openalex +1 more source
Management and Modification of Flavonoids Against Nonalcoholic Fatty Liver Disease
Flavonoids protect against NAFLD by enhancing mitochondrial function, reducing ER stress, and modulating gut microbiota. Structural modifications improve flavonoid efficacy, offering a promising dietary strategy for NAFLD management. ABSTRACT Flavonoids are small bioactive molecules commonly found in plant‐derived foods, exhibiting antioxidant, anti ...
Weidong Bai +6 more
wiley +1 more source
Peroxisome Dysfunction and Steatotic Liver Disease. [PDF]
Vinoy N +3 more
europepmc +1 more source

