Results 231 to 240 of about 42,473 (314)

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

A cryo-electron microscopy structure of yeast Pex5 in complex with a cargo uncovers a novel binding interface.

J Cell Sci
Peer L, Dym O, Elad N, Tirosh A, Jacobovitch J, Sivan E, Angel M, Albeck S, Schuldiner M, Peleg Y, Zalckvar E.   +10 more
europepmc   +1 more source

Mitochondrial and peroxisomal fission in cortical neurogenesis. [PDF]

Int J Biochem Cell Biol
Robertson GL, Bodnya C, Gama V.
europepmc   +1 more source

Characteristics, properties and limitations of per‐ or polyfluoroalkyl substances (PFASs) and fluoropolymers

Polymer International, EarlyView.
An overview and categorization of man‐made per‐ or polyfluoroalkyl substances (PFASs) including low‐molar‐mass and high‐molar‐mass fluorochemicals, and their international regulations is presented. Though certain PFASs are toxic, bioaccumulative and cross the human cellular membranes, others, such as fluoropolymers, are safe, reliable and involved in ...
Bruno Améduri
wiley   +1 more source

Quality control of ABCD3 by the VCP-FAF2 complex suppresses excessive pexophagy. [PDF]

Autophagy
Koyano F, Matsuda N.
europepmc   +1 more source

Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element.

, 1994
Ngoc Vu‐Dac, Kristina Schoonjans, Bernard Laine, Jean‐Charles Fruchart, Johan Auwerx, Bart Staels   +5 more
openalex   +1 more source

Impact of Epicatechin Supplementation on Plasma Proteome Profiles in Obese Men and Women—An Exploratory Approach to Sexual Dimorphism

PROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Purpose Evidence suggests that consuming epicatechin‐rich green tea can increase metabolism in the body, and this metabolic effect might be linked to weight loss in obese subjects. The precise mechanism by which epicatechin influences weight loss is still unclear.
Celso Pereira Batista Sousa‐Filho, Allanis Valon Ferreira, Leo Kei Iwai, Alison Felipe Alencar Chaves, Talita Souza Siqueira, Victoria Silva, Guilherme Ribeiro Romualdo, Rosemari Otton   +7 more
wiley   +1 more source

PEX11B palmitoylation couples peroxisomal dysfunction with Schwann cells fail in diabetic neuropathy. [PDF]

J Biomed Sci
Yang YM, Ma HB, Xiong Y, Wu Q, Gao XK.
europepmc   +1 more source

The SIRT1 N‐Terminal Domain as a Common Binding Interface for PPARγ Anchoring

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Insulin resistance, a global health threat linked to type 2 diabetes and obesity, can be addressed by modulating the activity of the Sirtuin 1 (SIRT1), a deacetylase that enhances insulin sensitivity by deacetylating the Peroxisome Proliferator‐Activated Receptor Gamma (PPARγ) at lysine 268 and 293. Understanding the binding interfaces between
Caique Camargo Malospirito, Gabriel Ernesto Jara, Víctor Ulian Antunes, Giovanna Blazutti Elias, Marieli Mariano Goncalves Dias, Fernanda Aparecida Heleno Batista, Paulo Sergio Lopes de Oliveira, Ana Carolina Migliorini Figueira   +7 more
wiley   +1 more source

Correlation of organelle interactions in the development of non-alcoholic fatty liver disease. [PDF]

Front Immunol
Liao J, Shao M, Zhou Z, Wang S, Lv Y, Lu Y, Yao F, Li W, Yang L.   +8 more
europepmc   +1 more source