Results 331 to 340 of about 125,831 (393)

MAVS oligomerization drives a faster and more efficient antiviral signaling activation at peroxisomes compared to mitochondria

The FEBS Journal, EarlyView.
Cells rely on mitochondria and peroxisomes to trigger antiviral defenses via the protein MAVS. This manuscript demonstrates that the robust production of antiviral effectors resulting from MAVS activation at peroxisomes is faster than at mitochondria due to a swifter oligomerization of this protein at peroxisomal membranes. These results underscore the
Bruno Ramos, Jéssica Sarabando, Mariana Marques, Jonathan C. Kagan, Daniela Ribeiro   +4 more
wiley   +1 more source

LAT1/SLC7A5‐mediated amino acid uptake is regulated by redox signals triggered by formyl‐peptide receptor 2

The FEBS Journal, EarlyView.
FPR2 activation mediates NOX‐dependent LAT1 expression and, in turn, promotes mTORC1 signaling. Upon stimulation with WKYMVm, the FPR2‐NOX2‐ROS axis upregulates LAT1 via increased c‐Myc phosphorylation and decreased miR‐126. Additionally, it promotes CD98 translocation to the plasma membrane.
Myrhiam Cassese, Chiara Brignola, Stefano Marrone, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo   +5 more
wiley   +1 more source

Zinc oxide nanoparticles disrupt peroxisome-endoplasmic reticulum contacts and increase very-long-chain fatty acid content. [PDF]

J Biol Chem
Zhong J, Liu X, Wang J, Liu H, Liu G, Wen X, Wu K.   +6 more
europepmc   +1 more source

A non-canonical fungal peroxisome PTS-1 signal, SYM, and its evolutionary aspects. [PDF]

Sci Rep
Ámon J, Nemuuzaya S, Alczheimer K, Kocsubé S, Farkas Z, Svorenj G, Gácser A, Tyagi C, Kozma-Bognár L, Hamari Z.   +9 more
europepmc   +1 more source

Bacterial pathogens hijack host cell peroxisomes for replication vacuole expansion and integrity. [PDF]

Sci Adv
Hossain MJ, Romanov KA, Jian J, Swaby LC, Bandyopadhyay S, Guan I, Thomas SM, Olive AJ, O'Connor TJ.   +8 more
europepmc   +1 more source

From Mitochondria to Immunity: The Emerging Roles of Mitochondria-Derived Vesicles and Small Extracellular Vesicles in Cellular Communication and Disease. [PDF]

J Extracell Vesicles
Horbay R, Syrvatka V, Bedzay A, van der Merwe M, Burger D, Beug ST.   +5 more
europepmc   +1 more source

The neurological pathology of peroxisomal ACBD5 deficiency - lessons from patients and mouse models. [PDF]

Front Mol Neurosci
Dawes ML, Haberlander JP, Islinger M, Schrader M.   +3 more
europepmc   +1 more source

Autophagy: The Last Antioxidant to Unravel. [PDF]

Antioxidants (Basel)
Fernández ÁF, García-Macia M.
europepmc   +1 more source

A cryo-electron microscopy structure of yeast Pex5 in complex with a cargo uncovers a novel binding interface.

J Cell Sci
Peer L, Dym O, Elad N, Tirosh A, Jacobovitch J, Sivan E, Angel M, Albeck S, Schuldiner M, Peleg Y, Zalckvar E.   +10 more
europepmc   +1 more source