Results 131 to 140 of about 84,481 (342)
See also article by Borbely et al. [9] (pages 225–233) in this issue. Peroxynitrite is a reactive nitrogen species (RNS) generated by the rapid, diffusionally controlled reaction of nitric oxide (NO) and superoxide [1]. Its formation has been implicated in many pathophysiological conditions such as ischemia–reperfusion, sepsis, and congestive heart
openaire +3 more sources
GA: Oxidative stress plays a critical role in Alzheimer's disease (AD) by promoting Aβ plaque accumulation and tau pathology, accelerating neurodegeneration. Elevated reactive oxygen species contribute to cognitive decline through extensive oxidative damage.
Abdüllatif Karakaya+8 more
wiley +1 more source
Tyrosine nitration in prostaglandin H2 synthase
In this study, we investigated the effects of various nitrogen oxide (NOx) species on the extent of prostaglandin H2 synthase-1 (PGHS-1) nitration in purified protein and in vascular smooth muscle cells.
Ruba S. Deeb+5 more
doaj
Mechanism of covalent modification of glyceraldehyde‐3‐phosphate dehydrogenase at its active site thiol by nitric oxide, peroxynitrite and related nitrosating agents [PDF]
Susanne Mohr+2 more
openalex +1 more source
Using the self-assembly of aromatic boronic acids with Alizarin Red S (ARS), we developed a new chemosensor for the selective detection of peroxynitrite.
Xiaolong Sun+8 more
semanticscholar +1 more source
Plasma‐activated water to foster sustainable agriculture: Evidence and quest for the fundamentals
An increasing world population facing limited natural resources poses a global challenge to food security. This challenge is increasing due to climate change, which in turn is strongly affected by the food system that accounts, according to the Food and Agriculture Organization (FAO), for one‐third of the global greenhouse gas emissions.
Vanni Antoni+2 more
wiley +1 more source
Schematic representation of how phytochemicals modulate miRNA expression to confer neuroprotection in cerebral ischemia. ABSTRACT Phytochemicals gained substantial interest for their protective action in cerebral ischemia. Additionally, there is a growing body of evidence suggesting that miRs play a role in stroke therapy. However, no systematic review
Joanna Rzemieniec+8 more
wiley +1 more source
Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction [PDF]
Jeffrey N. Keller+9 more
openalex +1 more source
Reaction of peroxynitrite with L-tryptophan
The reaction between peroxynitrous acid (hydrogen oxoperoxonitrate) and L-tryptophan is 130 M(-1)s(-1) at 25°C. The pH dependence of the second-order rate constant shows a maximum at pH 5.1. The enthalpy and entropy of activation at pH 7.1 are 10.6 ± 0.4 kcal.mol(-1) and -16 ± 2 cal.mol(-1)K(-1) respectively.
Willem H. Koppenol+3 more
openaire +4 more sources
Peroxynitrite and inflammatory bowel disease [PDF]
Idiopathic inflammatory bowel diseases (IBD), including ulcerative colitis and Crohn's disease, are chronic inflammatory disorders of the gastrointestinal tract which lead an unpredictable clinical course undergoing a succession of exacerbations and remissions of variable intensity.
openaire +3 more sources