Results 131 to 140 of about 84,481 (342)

Peroxynitrite like Pan? [PDF]

open access: yesCardiovascular Research, 2005
See also article by Borbely et al. [9] (pages 225–233) in this issue. Peroxynitrite is a reactive nitrogen species (RNS) generated by the rapid, diffusionally controlled reaction of nitric oxide (NO) and superoxide [1]. Its formation has been implicated in many pathophysiological conditions such as ischemia–reperfusion, sepsis, and congestive heart
openaire   +3 more sources

Design, Synthesis, In Silico Absorption, Distribution, Metabolism, and Elimination and Molecular Docking Studies of Thiazole‐Based Furan Derivatives, and Their Biological Evaluation for Alzheimer Disease Therapy

open access: yesChemistryOpen, EarlyView.
GA: Oxidative stress plays a critical role in Alzheimer's disease (AD) by promoting Aβ plaque accumulation and tau pathology, accelerating neurodegeneration. Elevated reactive oxygen species contribute to cognitive decline through extensive oxidative damage.
Abdüllatif Karakaya   +8 more
wiley   +1 more source

Tyrosine nitration in prostaglandin H2 synthase

open access: yesJournal of Lipid Research, 2002
In this study, we investigated the effects of various nitrogen oxide (NOx) species on the extent of prostaglandin H2 synthase-1 (PGHS-1) nitration in purified protein and in vascular smooth muscle cells.
Ruba S. Deeb   +5 more
doaj  

Reaction-based Indicator displacement Assay (RIA) for the selective colorimetric and fluorometric detection of peroxynitrite

open access: yesChemical Science, 2015
Using the self-assembly of aromatic boronic acids with Alizarin Red S (ARS), we developed a new chemosensor for the selective detection of peroxynitrite.
Xiaolong Sun   +8 more
semanticscholar   +1 more source

Plasma‐activated water to foster sustainable agriculture: Evidence and quest for the fundamentals

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
An increasing world population facing limited natural resources poses a global challenge to food security. This challenge is increasing due to climate change, which in turn is strongly affected by the food system that accounts, according to the Food and Agriculture Organization (FAO), for one‐third of the global greenhouse gas emissions.
Vanni Antoni   +2 more
wiley   +1 more source

Modulation of miRNAs by Phytochemicals in Cerebral Ischemia: A Systematic Review of In Vitro and In Vivo Studies

open access: yesPhytotherapy Research, EarlyView.
Schematic representation of how phytochemicals modulate miRNA expression to confer neuroprotection in cerebral ischemia. ABSTRACT Phytochemicals gained substantial interest for their protective action in cerebral ischemia. Additionally, there is a growing body of evidence suggesting that miRs play a role in stroke therapy. However, no systematic review
Joanna Rzemieniec   +8 more
wiley   +1 more source

Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction [PDF]

open access: hybrid, 1998
Jeffrey N. Keller   +9 more
openalex   +1 more source

Reaction of peroxynitrite with L-tryptophan

open access: yesRedox Report, 1996
The reaction between peroxynitrous acid (hydrogen oxoperoxonitrate) and L-tryptophan is 130 M(-1)s(-1) at 25°C. The pH dependence of the second-order rate constant shows a maximum at pH 5.1. The enthalpy and entropy of activation at pH 7.1 are 10.6 ± 0.4 kcal.mol(-1) and -16 ± 2 cal.mol(-1)K(-1) respectively.
Willem H. Koppenol   +3 more
openaire   +4 more sources

Peroxynitrite and inflammatory bowel disease [PDF]

open access: yesGut, 2000
Idiopathic inflammatory bowel diseases (IBD), including ulcerative colitis and Crohn's disease, are chronic inflammatory disorders of the gastrointestinal tract which lead an unpredictable clinical course undergoing a succession of exacerbations and remissions of variable intensity.
openaire   +3 more sources

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