Results 151 to 160 of about 46,884 (257)
MedComm, Volume 7, Issue 11, November 2026.This comprehensive review summarizes gastric cancer epidemiology, multifactorial risk factors (like infectious, dietary, genetic), pathogenesis such as precancerous evolution, molecular alterations, and a focus on the bidirectional interactions between gastric cancer cells and macrophages in the tumor microenvironment.
Yixuan Xin +6 more
wiley +1 more source
Peroxynitrite: A tale of two radicals
Redox Biochemistry and ChemistryThe published syntheses of peroxynitrite from azide, nitrite, amylnitrite, hydroxylamine, nitrogen monoxide, and ammonia are discussed. With one exception, all of these syntheses yield peroxynitrite contaminated with nitrate and nitrite as well as ...
Patricia L. Bounds, Willem H. Koppenol
doaj +1 more source
Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.Effects of thyroxine (T) and nano‐melatonin (NM) supplementation on cryopreserved Simmental bull semen were evaluated. The combination of thyroxine (0.5 µg/dL) and nano‐melatonin (30 µg/dL) significantly improved post‐thaw sperm motility, membrane integrity, antioxidant status, and fertility while reducing oxidative stress and apoptosis. These findings
Marwa Abonagy +18 more
wiley +1 more source
Janus Reactivity of a Mononuclear Non‐Heme Iron(III)‐Peroxo Complex Toward Indole Oxidation
Angewandte Chemie, Volume 138, Issue 43, 19 October 2026.The iron(III)‐peroxo complex [FeIII(O2)(12‐TMC)]+ exhibits bifurcating pathways in indole oxidation. N─H indoles undergo N─H H‐atom abstraction, supported by a KIE of 5.2 for N─H/N–D 2,3‐dimethylindoles, whereas N‐methylindoles react via electrophilic addition of the iron‐peroxo group to the C2–C3 double bond of the indole ring, forming iron ...
Wenjuan Zhu +4 more
wiley +2 more sources
Renin‐Angiotensin Signaling and Vascular Function: Insights into Health and Disease
Acta Physiologica, Volume 242, Issue 11, November 2026.ABSTRACT The renin‐angiotensin system (RAS) is an essential regulator of vascular structure and function, and dysregulation of angiotensin II (Ang II) signaling plays a critical role in the development of hypertension and associated vascular complications.
Giovanni Bertoldi, Swapnil K. Sonkusare
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 43, 19 October 2026.A series of Ir(III) complexes (Ir‐1‐Ir‐4) based on imidazole derivatives provide a new afterglow luminescence mechanism. The work expands the range of afterglow luminescence frameworks to overcome: (i) a lack of new afterglow scaffolds; (ii) the dependence on initial external light activation; and (iii) aggregation‐caused quenching.
Zihan Wu +9 more
wiley +2 more sources
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.ABSTRACT N‐acetyl‐p‐aminophenol (APAP), or acetaminophen, is the most prescribed analgesic and antipyretic, even used in association with other drugs. Because it is easily bought in drugstores, much evidence about its toxic effects is known due to high doses or continuous use, which can lead to death in cases of intoxication.
Alex Luiz Menezes da Silva +9 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 21, Page 6371-6385, November 2026.Background and Purpose The persistence of temporomandibular disorders (TMDs), particularly myogenous, in a person with migraine can lead to exacerbated clinical outcomes and limited response to treatment. The pro‐nociceptive reactive nitroxidative species, peroxynitrite, is involved in migraine mechanisms, but little is known of its role in this ...
Simon Akerman +4 more
wiley +1 more source
Lipoprotein(a), Endothelial Dysfunction and Cardiovascular Disease
Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.ABSTRACT Lipoprotein(a) (Lp(a)) is a particle similar to low‐density lipoprotein cholesterol and is associated with apolipoprotein (A). High Lp(a) levels are a genetic, independent risk factor for atherosclerotic cardiovascular disease (ASCVD). Endothelial cells, which form the continuous lining of the cardiovascular system, are crucial for vascular ...
Xianghui Zhou +5 more
wiley +1 more source
Experimental Physiology, Volume 111, Issue 11, Page 5154-5165, 1 November 2026.Abstract A lack of consensus remains on whether normobaric hypoxia (NH) and hypobaric hypoxia (HH) may differentially impact physiological factors affecting cerebrovascular regulation, particularly with an additional strenuous exercise component. We sought to compare the acute effects of NH and HH on global cerebral blood flow (gCBF) at an altitude ...
Rachel Turner +3 more
wiley +1 more source