Results 131 to 140 of about 46,884 (257)
CO2 impairs peroxynitrite-mediated inhibition of human caspase-3.
Peroxynitrite (ONOO-) is a transient powerful oxidant produced in vivo as the reaction of nitrogen monoxide (.NO) with superoxide (O2.-). The peroxynitrite reactivity is modulated by carbon dioxide (CO2) which enhances the peroxynitrite-mediated ...
MARINO, Maria, Ascenzi P, Menegatti E.
core
Cellular mechanisms of peroxynitrite-induced neuronal death
Peroxynitrite (ONOO−) is a strong biological oxidant formed by the diffusion-limited reaction of nitric oxide (NO−) and superoxide anion (O2[rad]−). It has long been theorized that peroxynitrite generation could be the cause in a number of pathological ...
Kristina Ramdial +5 more
core +1 more source
A nanomodulator called L‐Arginine/lificiguat@Copper‐hollow Prussian blue@Calcium phosphate nanoparticles is constructed to launch a self‐amplifying “avalanche effect” in tumor cells. The ensuing cascade, triggered by the acidic tumor microenvironment and near‐infrared light, induces calcium overload, generates a reactive oxygen species and reactive ...
Hongmei Zhou +9 more
wiley +1 more source
Real‐Time Neurochemical Sensing in Zebrafish: Electrochemical and Fluorescent Approaches
The use of zebrafish has emerged as a powerful approach for real‐time neurochemical measurements. This review highlights recent advances in electrochemical and fluorescent sensing strategies that enable dynamic measurements in live preparations of this complex vertebrate. These complementary approaches provide new insights into neurochemical signaling,
Piyanka Hettiarachchi +2 more
wiley +1 more source
A peroxynitrite-specific two-photon fluorescent probe was developed for revealing drug-induced hepatotoxicity using peroxynitrite as a biomarker.
Xilei Xie +7 more
core +1 more source
Curcumin Intervention in Diabetic Neuropathy: Molecular Mechanisms and Preclinical Insights
This review highlights curcumin's neuroprotective potential, showing how it mitigates oxidative stress and inflammation by modulating Nrf2, MAPK, and NF‐κB signaling. Preclinical data shows it stabilizes glucose metabolism and reduces nerve degradation.
Sanket Sharma +5 more
wiley +1 more source
Apocynin inhibits peroxynitrite formation by murine macrophages
1 Peroxynitrite (ONOO-) the highly reactive coupling product of nitric oxide and superoxide, has been implicated in the pathngenesis of an increasing number of (inflammatory) diseases. At present, however. selective peroxynitrite antagonizing agents with
Muijsers, RBR +6 more
core +1 more source
The photolysis of potassium, rubidium and cesium crystalline nitrates under light with the photon energy of 5.58 eV was investigated. Nitrite and peroxynitrite are the photolysis end-products.
L. D. Kriger +2 more
doaj
Inflammation and Oxidative Damage in Fatty Acids Oxidation Disorders
ABSTRACT Deficiencies in enzymes and transporters involved in mitochondrial fatty acid beta oxidation results in the accumulation of fatty acids, a condition known as fatty acid oxidation disorders (FAODs). Therefore, the present study aimed to evaluate the oxidative and inflammatory profiles of treated patients with FAODs, comparing those receiving ...
Stefani Altenhofen +11 more
wiley +1 more source

