Results 141 to 150 of about 46,884 (257)
HKGreen-3: A rhodol-based fluorescent probe for peroxynitrite
, 2010 A novel fluorescent probe, HKGreen-3, for sensing peroxynitrite is designed on the basis of the rhodol scaffold and a peroxynitrite-specific oxidation reaction.
Yang, D, Peng, T, Tao Peng, Dan Yang
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Advances in Multidimensional Molecular Mechanisms of Epilepsy and Precision Therapy Strategies
CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.Epilepsy arises from a multidimensional network imbalance, integrating genetic, inflammatory, and metabolic disruptions. This complexity drives neuronal hyperexcitability and underpins therapeutic challenges. Our review highlights how emerging precision strategies, from targeted molecular therapies to neuromodulation, offer a transformative path toward
Yimin Han +7 more
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Effects of peroxynitrite on the reactivity of diabetic rat aorta
, 2001 Endogenous nitric oxide (NO) reacts with superoxide to form peroxynitrite, which is capable of either oxidizing or nitrating various biological substrates.
Karasu, ÇİMEN, Cakici, I, Zobali, F
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The Role of Mitochondrial Homeostasis in the Pathogenesis of Chronic Rhinosinusitis
Immunity, Inflammation and Disease, Volume 14, Issue 11, November 2026.The vicious cycle between pathogenic factors‐induced inflammation, oxidative stress, and mitochondrial dysfunction in the context of chronic rhinosinusitis. Created in BioRender. Taghizadeh‐Hesary (2026) https://BioRender.com/k5f4t1f. ABSTRACT Background Chronic rhinosinusitis (CRS) is a common clinical condition characterized by persistent ...
Babak Ghalehbaghi +6 more
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The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite 'scavenger'?
, 2004 Hydrogen sulfide (H2S) is a well-known cytotoxic gas. Recently it has been shown to stimulate N-methyl-D-aspartate (NMDA) receptors to enhance long-term potentiation suggesting a novel neuromodulatory role in vivo.
Siau, JL (15527186) +7 more
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Actomyosin modulation by peroxynitrite [PDF]
, 2007 In the present work we address the oxidative modifications accounting for the structural and functional impairment of the actomyosin complex under the oxidative stress mediated by peroxynitrite (ONOO-). Experiments on purified myosin and actin have shown
Gutiérrez-Merino, Carlos +4 more
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Journal of Applied Toxicology, Volume 46, Issue 11, Page 3868-3881, November 2026.ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima +4 more
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Highly efficient and stable catalyst for peroxynitrite decomposition
, 2001 The new cobalt substituted-polyoxometalate K7[CoAlW11O39]·15H2O and the simple CoCl2·6H2O salt are efficient catalysts for peroxynitrite decomposition.
Jennifer J Cowan +4 more
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Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.Betaine helps to restore the dysfunctional communication between oxidative stress and inflammation, and it also improves demyelination in cuprizone‐induced demyelinating disease within the cerebral cortex. ABSTRACT Cortical grey matter pathology manifests early demyelinating diseases and is a primary driver of permanent neurological impairment.
Yara M. Said +4 more
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Attenuation of vascular relaxation after development of tachyphylaxis to peroxynitrite in vivo
, 1998 Peroxynitrite, formed endogenously by the near diffusion-limited reaction of nitric oxide with superoxide anion, induces vascular relaxation. This effect is subject to rapid tachyphylaxis, suggesting that peroxynitrite may alter subsequent vasorelaxant ...
Neil W. Kooy +2 more
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