Results 141 to 150 of about 84,481 (342)
Mitochondrial dynamics in autoimmune diseases
Rheumatology &Autoimmunity, EarlyView.Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma +5 more
wiley +1 more source
Journal of Pharmacological Sciences, 2009 We have previously reported that peroxynitrite is involved in dysfunction of nitric oxide (NO)-mediated vasorelaxation in SHR/NDmcr-cp rats (SHR-cp), which display typical symptoms of metabolic syndrome.
Satomi Kagota +5 more
doaj
Oxyleghemoglobin scavenges nitrogen monoxide and peroxynitrite: a possible role in functioning nodules? [PDF]
, 2018 It has been demonstrated that the NO• produced by nitric oxide synthase or by the reduction of nitrite by nitrate reductase plays an important role in plants' defense against microbial pathogens.
Herold, Susanna, Puppo, Alain
core
Smart Molecules, EarlyView.A new class of photoactivatable peroxynitrite (ONOO−) donors based on a single rhodamine scaffold enables spatiotemporally controlled ONOO− release with fluorescence calibration, offering a powerful tool for probing ONOO− biology and redox signaling in live cells.
Mengqi Liu +8 more
wiley +1 more source
Increasing Tetrahydrobiopterin in Cardiomyocytes Adversely Affects Cardiac Redox State and Mitochondrial Function Independently of Changes in NO Production [PDF]
, 2016 Tetrahydrobiopterin (BH4) represents a potential strategy for the treatment of cardiac remodeling, fibrosis and/or diastolic dysfunction. The effects of oral treatment with BH4 (Sapropterin™ or Kuvan™) are however dose-limiting with high dose negating ...
Bennett, Brian +5 more
core +1 more source
Small Science, EarlyView.This article discusses the preparation methods, structural engineering, and key properties of transition metal nitrides, as well as their versatile applications in supercapacitors, rechargeable batteries, electrocatalytic and photocatalytic processes, and solar cell technologies.
Narasimharao Kitchamsetti +2 more
wiley +1 more source
Decreased Zinc Affinity of Amyotrophic Lateral Sclerosis‐Associated Superoxide Dismutase Mutants Leads to Enhanced Catalysis of Tyrosine Nitration by Peroxynitrite [PDF]
, 1997 John P. Crow +4 more
openalex +1 more source
Small Structures, EarlyView.Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou +8 more
wiley +1 more source
2,7‐Dihydrodichlorofluorescein diacetate as a fluorescent marker for peroxynitrite formation [PDF]
, 1997 Heiko Possel +4 more
openalex +1 more source
VIEW, EarlyView.Our findings demonstrate that NAD+ metabolism dysregulation contributes to elevated intraocular pressure in glaucoma. Supplementation with NAD+ precursors reduces IOP by alleviating oxidative stress, cellular senescence, and extracellular matrix deposition.
Youjia Zhang +10 more
wiley +1 more source