Results 181 to 190 of about 84,481 (342)
Generation of peroxynitrite contributes to ischemia-reperfusion injury in isolated rat hearts [PDF]
, 1997 William MacNee Yasmin
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The Journal of Physiology, EarlyView.Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida +4 more
wiley +1 more source
Direct EPR detection of the carbonate radical anion produced from peroxynitrite and carbon doxide.
, 1999 Marcelo G. Bonini +4 more
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Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury
The Journal of Physiology, EarlyView.Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich +5 more
wiley +1 more source
Inhibitory effect of calotropis gigantea extract on ovalbumin-induced airway inflammation and arachidonic acid induced inflammation in a murine model of asthma [PDF]
, 2011 The root of Calotropis gigantea has been reported as a traditional folkloric medicine in treatment of asthma in the Indian literature. Root contain α-and β-amyrin are reported to possess anti-lipoxygenase activity.
Vipin Bulani, Kailash Biyani, Ravindra Kale, Unmesh Joshi, Kishor Charhate, Dinesh Kumar, Ramesh Pagore, Int J Cur Bio Med Sci.
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The formation of nitric oxide donors from peroxynitrite [PDF]
, 1995 Marı́a A. Moro +6 more
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The Journal of Physiology, EarlyView.Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu +7 more
wiley +1 more source
Interaction of Peroxynitrite with Mitochondrial Cytochrome Oxidase [PDF]
, 1998 Martyn A. Sharpe, Chris E. Cooper
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MedComm – Biomaterials and Applications, Volume 4, Issue 3, September 2025.This review highlights pathological features of diabetic wounds, and explores the design principles and therapeutic strategies of smart responsive hydrogels. Importantly, the review evaluates the challenges associated with these technologies and outlines future engineering directions to optimize their clinical adoption.
Jiyuan Du +5 more
wiley +1 more source