Results 191 to 200 of about 84,481 (342)

Matrix metalloproteinase inhibition protects against junctophilin‐2 proteolysis during doxorubicin‐induced cardiotoxicity

British Journal of Pharmacology, Volume 182, Issue 17, Page 4103-4121, September 2025.
Abstract Background and Purpose Treatment of cancer patients with anthracyclines is known to cause dose‐dependent cardiotoxicity through several mechanisms including enhanced oxidative stress, ultimately resulting in defective excitation–contraction coupling.
Wesam Bassiouni, Brandon Y. H. Chan, Andrej Roczkowsky, Joshua W. Kranrod, Zabed Mahmud, Joseph O. Primeau, Woo Jung Cho, Howard S. Young, John M. Seubert, Richard Schulz   +9 more
wiley   +1 more source

Activation pattern of mitogen‐activated protein kinases elicited by peroxynitrite: attenuation by selenite supplementation [PDF]

, 1999
Stefan M. Schieke, Karlis Briviba, Lars‐Oliver Klotz, Helmut Sies   +3 more
openalex   +1 more source

Evidence for iNOS-dependent peroxynitrite production in diabetic platelets [PDF]

, 1999
Maria Tannous, R. A. Rabini, Arianna Vignini, N. Moretti, P. Fumelli, Barbara S. Zielinski, Laura Mazzanti, Bülent Mutus   +7 more
openalex   +1 more source

Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide.

Journal of Biological Chemistry, 1991
Rafael Radil, J. Beckman, K. Bush, B. Freeman   +3 more
semanticscholar   +1 more source

Hydrogen Sulfide Protects Erectile Function Through Stimulation of Antioxidant Defense in the Corpus Cavernosum: Insights From SG1002 Administration and Cystathionine γ‐Lyase Knockout

The FASEB Journal, Volume 39, Issue 15, 15 August 2025.
Chronic consumption of a western diet suppressed corpus cavernosum cystathionine γ‐lyase (CSE) protein content and H2S production and was associated with elevated penile reactive oxygen species (ROS) levels and impaired erectile function. CSE knockout mice demonstrate impaired erectile function, elevated penile ROS levels, and suppressed corpus ...
Tooyib A. Azeez, Paige R. Rhein, Clifford J. Pierre, Colin M. Ihrig, Justin D. La Favor   +4 more
wiley   +1 more source

Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease [PDF]

, 1998
King-Teh Lin, Jiyan Xue, Marie C. Lin, Eric G. Spokas, Frank F. Sun, Patrick Y.-K. Wong   +5 more
openalex   +1 more source

Curcumin Promotes the Recovery of Motor Function After Brachial Plexus Avulsion Injury in Rats

Brain and Behavior, Volume 15, Issue 8, August 2025.
CUR promotes the recovery of motor function in rats after BPRA by inhibiting inflammation, promoting axonal remyelination, and reducing muscle atrophy, laying a foundation for the treatment of BPRA with CUR. ABSTRACT Background and Purpose Brachial plexus root avulsion (BPRA) often results in the loss of upper limb motor function.
Sijing Li, Bing He, Guijuan Zhou, Lin Wu, Xuanwei Wen, Limin Deng, Shudong Lin, Guozhi Liu, Shuangxi Chen, Zijian Xiao   +9 more
wiley   +1 more source

Role of Peroxynitrite as a Mediator of Pathophysiological Alterations in Experimental Pneumococcal Meningitis [PDF]

, 1999
Stefan Kastenbauer, Uwe Koedel, Hans‐Walter Pfister   +2 more
openalex   +1 more source

Phenolic Compounds in Exercise Physiology: Dual Role in Oxidative Stress and Recovery Adaptation

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
Exercise increases mitochondrial activity and reactive oxygen species (ROS) production, which can lead to oxidative stress. However, phenolic compounds act as potent antioxidants, counteracting ROS and thereby mitigating oxidative stress. This graphical abstract illustrates the dual role of exercise and dietary antioxidants in the regulation of redox ...
Kübra Özdemir, Yeliz Demir
wiley   +1 more source

Nanomedical studies of the restoration of nitric oxide/peroxynitrite balance in dysfunctional endothelium by 1,25-dihydroxy vitamin D3 – clinical implications for cardiovascular diseases

International Journal of Nanomedicine, 2018
Alamzeb Khan, Hazem Dawoud, Tadeusz Malinski Department of Chemistry & Biochemistry, Nanomedical Research Laboratories, Ohio University, Athens, OH, USA Background: Clinical studies indicate that vitamin D3 improves circulation and may have ...
Khan A, Dawoud H, Malinski T
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