Results 41 to 50 of about 76,980 (312)

Analysis of acid-stressed Bacillus cereus reveals a major oxidative response and inactivation-associated radical formation [PDF]

, 2010
Acid stress resistance of the food-borne human pathogen Bacillus cereus may contribute to its survival in acidic environments, such as encountered in soil, food and the human gastrointestinal tract. The acid stress responses of B.
Abee, T., Kranenburg, R., van, Melis, C.C.J., van, Moezelaar, R., Mols, J.M.   +4 more
core   +2 more sources

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Peroxynitrite-induced hemolysis of human erythrocytes and its inhibition by antioxidants [PDF]

, 1997
It was found that human erythrocytes underwent hemolysis when incubated with peroxynitrite at 37°C under air. The extent of hemolysis increased with increasing peroxynitrite concentration and decreasing hematocrit. The peroxynitrite-induced hemolysis was
Hiroshi Kondo, Mareyuki Takahashi, Etsuo Niki, Moncada, Beckman, Pryor, Radi, Darley-Usmar, Rubbo, Jessup, Hogg, Hayashi, Yamamoto, Niki, Miki, Sandhu, Miki, Ellman, Yamamoto, Niki, Feelish, Whiteman, Salgo, Sies, Masumoto, Jia   +25 more
core   +2 more sources

Cyclic Hydroxylamines as Monitors of Peroxynitrite and Superoxide-Revisited

Antioxidants, 2021
There is a considerable need for methods that allow quantitative determination in vitro and in vivo of transient oxidative species such as peroxynitrite (ONOOH/ONOO−) and superoxide (HO2•/O2•−).
Uri Samuni, Amram Samuni, Sara Goldstein
doaj   +1 more source

T-cadherin deficiency increases vascular vulnerability in T2DM through impaired NO bioactivity. [PDF]

, 2017
BACKGROUND: Endothelial dysfunction plays a critical role in the development of type 2 diabetes (T2DM). T-cadherin (T-cad) has gained recognition as a regulator of endothelial cell (EC) function.
Ambrosio, Anastasia, Lau, Wayne Bond, Ma, Xin-Liang, Summer, Ross, Tao, Ling, Wang, Han, Wang, Yajing, Yan, Wenjun   +7 more
core   +2 more sources

Peroxynitrite-Mediated Mitochondrial Dysfunction

Neurosignals, 2001
Peroxynitrite anion (ONOO(-)) is a potent biological oxidant produced by the near diffusion-limited reaction of superoxide and nitric oxide. Peroxynitrite has been implicated in diverse forms of free radical-induced tissue injury. Experimental evidence showed that exogenous and endogenous peroxynitrite causes alterations of the structure and function ...
J, Boczkowski, C L, Lisdero, S, Lanone, M C, Carreras, M, Aubier, J J, Poderoso   +5 more
openaire   +2 more sources

Exercise redox biochemistry:conceptual, methodological and technical recommendations [PDF]

, 2017
Exercise redox biochemistry is of considerable interest owing to its translational value in health and disease. However, unaddressed conceptual, methodological and technical issues complicate attempts to unravel how exercise alters redox homeostasis in ...
Bailey, Damian M., Close, Graeme L., Cobley, James N., Davison, Gareth W.   +3 more
core   +7 more sources

Effects of urate, a natural inhibitor of peroxynitrite-mediated toxicity, in the response of Arabidopsis thaliana to the bacterial pathogen Pseudomonas syringae [PDF]

, 2001
Urate, a natural peroxynitrite scavenger, has been used to investígate the possible role of peroxynitrite during plant-pathogen interactions. Urate greatly reduced lesión formation in Arabidopsis leaves treated with an abiotic peroxynitrite-generating ...
Allan, Alvarez, Ausubel, Baker, Balavoine, Beligni, Bennett, Bestwick, Blumwald, Bolwell, Bolwell, Brown, Crawford, Dangl, Delledonne, Durner, Durner, Favey, Foissner, Francisco García-Olmedo, Gardner, Hammond-Kosack, Hooper, Jabs, Josefa M. Alamillo, Kado, Keller, Keogh, Kiedrowski, King, Lagrimini, Lamb, Levine, Lipton, Liu, Lummerzhein, Marla, McLusky, O'Neil, Polle, Pontier, Radi, Regoli, Schubert, Skinner, Stamler, Stamler, Summermatter, Torres, Turner, Uknes, Vasquez-Vivar, Whiteman, Williamson, Wink, Yu   +55 more
core   +2 more sources

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Formation of 2-nitrophenol from salicylaldehyde as a suitable test for low peroxynitrite fluxes

Redox Biology, 2016
There has been some dispute regarding reaction products formed at physiological peroxynitrite fluxes in the nanomolar range with phenolic molecules, when used to predict the behavior of protein-bound aromatic amino acids like tyrosine.
Yuliya Mikhed, Kai Bruns, Stefan Schildknecht, Michael Jörg, Mobin Dib, Matthias Oelze, Karl J. Lackner, Thomas Münzel, Volker Ullrich, Andreas Daiber   +9 more
doaj   +1 more source