Results 21 to 30 of about 46,884 (257)
N-Nitroso products from the reaction of indoles with Angeli's salt [PDF]
, 2006 While nitroxyl (HNO) has been shown to engage in oxidation and hydroxylation reactions, little is known about its nitrosating potential. We therefore sought to investigate the kinetics of formation and identity of the reaction products of the classical ...
Peyrot, Fabienne +11 more
core +1 more source
A Diazaborine-Based Fluorescent Probe Tracks Endogenously Produced Peroxynitrite in Live Cells [PDF]
, 2022 We present the synthesis, properties, and imaging applications of Peroxynitrite Probe-1 (PNP-1), a novel organoboron-based probe for selective peroxynitrite (ONOO-) imaging in live cells.
Dylan, Domaille, Jack, Haggett
core +2 more sources
Local oxidative and nitrosative stress increases in the microcirculation during leukocytes-endothelial cell interactions. [PDF]
PLoS ONE, 2012 Leukocyte-endothelial cell interactions and leukocyte activation are important factors for vascular diseases including nephropathy, retinopathy and angiopathy.
Saptarshi Kar, Mahendra Kavdia
doaj +1 more source
Myoglobin Scavenges Peroxynitrite without Being Significantly Nitrated
, 2016 We have analyzed in detail hemoglobin (Hb) and myoglobin (Mb) after treatment of different forms of these proteins with variable amounts of peroxynitrite.
Susanna Herold (2698546) +2 more
core +3 more sources
Pakistan Journal of Pharmaceutical Sciences, 2020 Peroxynitrite is known as a strong deleterious species that may readily trigger several geriatric diseases via injuring cellular constituents. Proanthocyanidins, a biological flavonoids constituent of Pinus sylvestris L. bark, has been attributed a large
Qingfeng HE +4 more
doaj +1 more source
Red Blood Cell Peroxynitrite Causes Endothelial Dysfunction in Type 2 Diabetes Mellitus via Arginase
Cells, 2020 We recently showed that red blood cells (RBCs) from patients with type 2 diabetes mellitus (T2DM-RBCs) induce endothelial dysfunction through a mechanism involving arginase I and reactive oxygen species.
Ali Mahdi +5 more
doaj +1 more source
BMC Neuroscience, 2002 Background Oxidative stress has shown to contribute in the mechanisms underlying apoptotic cell death occuring in AIDS-dementia complex. Here we investigated the role of peroxynitrite in apoptosis occurring in astroglial cells incubated with supernatants
Perno Carlo +9 more
doaj +1 more source
CARDIOVASCULAR EFFECTS OF PEROXYNITRITE [PDF]
Clinical and Experimental Pharmacology and Physiology, 2007 SUMMARYPeroxynitrite (PN) is formed in biological systems from the reaction of nitric oxide (·NO) with superoxide (·) and both exist as free radicals. By itself, PN is not a free radical, but it can generate nitrogen dioxide (·NO2) and carbonate radical (·) upon reaction with CO2.The reaction of CO2constitutes a major pathway for the disposition of PN ...
Rao M, Uppu +6 more
openaire +2 more sources
The evolutionary origins of peroxynitrite signalling [PDF]
Biochemical and Biophysical Research Communications, 2021 Peroxynitrite is a reactive intermediate formed in vivo through uncatalysed reaction of superoxide and nitric oxide radicals. Despite significant interest in detecting peroxynitrite in vivo and understanding its production, little attention has been given to the evolutionary origins of peroxynitrite signalling.
Jennifer A. Miles +7 more
openaire +3 more sources
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source