Results 111 to 120 of about 2,213,349 (340)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Bordetella petrii Infection with Long-lasting Persistence in Human
Emerging Infectious Diseases, 2011 We report the repeated isolation of Bordetella petrii in the sputum of a 79-year-old female patient with diffuse bronchiectasis and persistence of the bacterium for >1 year.
Alain Le Coustumier +4 more
doaj +1 more source
Intracellular Pathogens: Host Immunity and Microbial Persistence Strategies
Journal of Immunological Research, 2019 Infectious diseases caused by pathogens including viruses, bacteria, fungi, and parasites are ranked as the second leading cause of death worldwide by the World Health Organization.
Aneesh Thakur +2 more
semanticscholar +1 more source
The changing dynamics of US inflation persistence : a quantile regression approach : [Version 4 September 2012] [PDF]
, 2012 We examine both the degree and the structural stability of inflation persis tence at different quantiles of the conditional inflation distribution.
Tillmann, Peter, Wolters, Maik Hendrik
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Ciência Rural, 2001 No presente trabalho, avaliou-se o efeito residual dos herbicidas imazaquin (150 e 300g de equivalente ácido ha-1) e alachlor+atrazine (1430+1430 e 2860+2860g ha-1), aplicados respectivamente em soja e milho, visando a determinar o intervalo de tempo ...
Rubem Silvério de Oliveira Júnior
doaj +1 more source
Improving Underrepresented Minority Student Persistence in STEM
CBE - Life Sciences Education, 2016 Members of the Joint Working Group on Improving Underrepresented Minorities (URMs) Persistence in Science, Technology, Engineering and Mathematics (STEM), utilizing Kurt Lewin’s planned approach to change, describe five recommendations to increase URM ...
M. Estrada +15 more
semanticscholar +1 more source