Results 91 to 100 of about 16,153 (254)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ovariectomy improves lactation persistency in dairy cows

, 2012
Chantier qualité GAA current trend in the dairy industry is to reduce milk yield at the peak of lactation and improve lactation persistency. Lactation persistency is influenced by livestock management factors, such as feeding level or milking frequency ...
Dessauge, Frederic, Marnet, Pierre-Guy, Lollivier, Vanessa, Finot, Laurence, Yart, Lucile, Barbey, S.   +5 more
core   +1 more source

Study of individual lactation patterns of Iranian dairy buffaloes

Journal of Agriculture and Rural Development in the Tropics and Subtropics, 2014
The aims of the current study were 1) to investigate the effects of some environmental factors on lactation curve traits (LCTs) including initial milk yield (A), peak yield (PY), days to attain peak yield (PD), inclining- and declining slope of lactation
Borhan Shokrollahi, Karim Hasanpour
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Measures of Dogs' Inhibitory Control Abilities Do Not Correlate across Tasks

Frontiers in Psychology, 2017
Inhibitory control, the ability to overcome prepotent but ineffective behaviors, has been studied extensively across species, revealing the involvement of this ability in many different aspects of life. While various different paradigms have been created
Désirée Brucks, Sarah Marshall-Pescini, Lisa Jessica Wallis, Lisa Jessica Wallis, Ludwig Huber, Friederike Range   +5 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Verification under Intel-x86 with Persistency

The full semantics of the Intel-x86 architecture has been defined by Raad et al in POPL 2022, extending the earlier formalization based on the TSO memory model incorporating persistency. This new semantics involves an intricate combination of the SC, TSO,
Atig, Mohamed Faouzi,, Kumar, K. Narayan,, Saivasan, Prakash,, Bouajjani, Ahmed, Atig, Mohamed Faouzi, Abdulla, Parosh, Saivasan, Prakash, Bouajjani, Ahmed,, Kumar, K. Narayan, Abdulla, Parosh,   +9 more
core   +1 more source

Spot ve Future Piyasalar Arasındaki Oynaklık Yayılımları ve Yayılımların Kalıcılığının Analizi

Ekonomi, Politika & Finans Araştırmaları Dergisi
Future piyasalar ve dayanak varlığa ait spot piyasalar birbiriyle yakından ilişkilidir. Bu ilişkiler fiyatlar ve getiriler bazında veya risk geçişleri olarak gözlemlenmektedir.
Tuba Sevil, Fatih Temizel, Melik Kamışlı, Güven Sevil, Serap Kamışlı   +4 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source