Results 111 to 120 of about 13,899 (258)
Persistency in lactation – a review
, 2005 Persistency in lactation can be defined as the capacity of a cow to maintain her milk yield after reaching the maximum level early lactation. Several studies document the existence of genetic differences among animals for persistency in lactation.
Costa, C. N. +5 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Testing for Yield Persistency: Is It Skill or is It Luck?
This study uses corn yield data from McLean County, Illinois to test whether farmer skill influences yields. This analysis is conducted by performing persistency tests on unadjusted, soil productivity adjusted (PA), and productivity and input intensity ...
Schnitkey, Gary D. +3 more
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Do shocks last forever? Local persistency in economic time series
, 2007 While it is recognized that many macroeconomic time series are highly persistent over certain range, less persistent results are also found around very long horizons, indicating the existence of local or temporary persistency.
Xiao, Zhijie +1 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The Logic of Belief Persistency
, 1995 The interaction bietween knowledge and belief in a temporal context is analyzed. An axiomatic formulation and semantic characterization of the principle of belief persistency implied by the standard conditionalization rule are provided.
Battigalli, Pierpaolo, Bonanno, Giacomo
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A Multivariate measure of lactation persistency for dairy sheep [PDF]
, 2003 The persistency of lactation,i.e. the ability of animals to maintain a rconstant level of production after the lactation peak, represents an interesting trait for animal breeding strategies, allowing for the increase of profitability of animal husbandry ...
Macciotta, Nicolò Pietro Paolo +3 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Persistency in Malaysian higher education [PDF]
, 2010 Higher Education (HE) is becoming an increasingly complex phenomenon throughout the world due to observable major contemporary trends such as diversification, privatization, globalization and internalization.
Ghafar, Mohd. Najib +1 more
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