Results 121 to 130 of about 16,153 (254)
Investigation of Factors Influencing Lactation Persistency in the Goat [PDF]
, 1996 This thesis examines some of the factors which play a role in determining lactation persistency in the goat with the overall aim of improving persistency.
Brown, Joanna R
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Persistency in Malaysian higher education [PDF]
, 2010 Higher Education (HE) is becoming an increasingly complex phenomenon throughout the world due to observable major contemporary trends such as diversification, privatization, globalization and internalization.
Ghafar, Mohd. Najib +1 more
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Persistency Model and Its Applications in Choice Modeling
, 2009 Given a discrete maximization problem with a linear objective function where the coefficients are chosen randomly from a distribution, we would like to evaluate the expected optimal value and the marginal distribution of the optimal solution.
Teo, C.-P. +6 more
core +1 more source
A parametric measure of lactation persistency in dairy cattle
, 2013 Current measures of lactation persistency are not uniformly applicable to the variety of lactation curves for individual cows. Moreover, they are either difficult to interpret or are functions of lactation yield and therefore inappropriate. In this study,
Kamidi, R.E.
core +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
A Multivariate measure of lactation persistency for dairy sheep [PDF]
, 2003 The persistency of lactation,i.e. the ability of animals to maintain a rconstant level of production after the lactation peak, represents an interesting trait for animal breeding strategies, allowing for the increase of profitability of animal husbandry ...
Macciotta, Nicolò Pietro Paolo +3 more
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