Results 91 to 100 of about 1,043,448 (307)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Gene Coexpression Network Comparison via Persistent Homology
International Journal of Genomics, 2018 Persistent homology, a topological data analysis (TDA) method, is applied to microarray data sets. Although there are a few papers referring to TDA methods in microarray analysis, the usage of persistent homology in the comparison of several weighted ...
Ali Nabi Duman, Harun Pirim
doaj +1 more source
Topological variability in financial markets
Quantitative Finance and Economics, 2023 We investigate market crashes and downturns through the lens of persistent homology and persistence landscape norms. Using individual stock price data from Yahoo!
Aaron D Valdivia
doaj +1 more source
Nori Diagrams and Persistent Homology [PDF]
Mathematics in Computer Science, 2019 45 ...
Manin, Yuri I., Marcolli, Matilde
openaire +5 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
ExperimedObjective: This study aimed to use a new approach, namely persistent homology, to analyse electroen cephalogram (EEG) coherence and identify the alterations in brain connectivity in patients with Alzheimer’s disease (AD).Materials and Methods: We applied
Atilla Uslu +3 more
doaj +1 more source
Stochastic convergence of persistence landscapes and silhouettes
Journal of Computational Geometry, 2015 Persistent homology is a widely used tool in Topological Data Analysis that encodes multi-scale topological information as a multiset of points in the plane called a persistence diagram.
Frédéric Chazal +4 more
doaj +1 more source
Cubical Homology-Based Machine Learning: An Application in Image Classification
Axioms, 2022 Persistent homology is a powerful tool in topological data analysis (TDA) to compute, study, and encode efficiently multi-scale topological features and is being increasingly used in digital image classification.
Seungho Choe, Sheela Ramanna
doaj +1 more source
PHAT – Persistent Homology Algorithms Toolbox
Journal of Symbolic Computation, 2014 Phat is an open-source C++ library for the computation of persistent homology by matrix reduction, targeted towards developers of software for topological data analysis. We aim for a simple generic design that decouples algorithms from data structures without sacrificing efficiency or user-friendliness.
Bauer, Ulrich +3 more
openaire +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source