Results 81 to 90 of about 1,143,028 (268)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Frontiers in Aging Neuroscience, 2020 Current researches on default mode network (DMN) in normal elderly have mainly focused on finding some dysfunctional areas with decreased or increased connectivity. The global network dynamics of apolipoprotein E (APOE) e4 allele group is rarely studied.
Liqun Kuang +6 more
doaj +1 more source
SN Computer Science, 2023 In this work, we present a combination of dimension reduction techniques and persistent homology for detection of epileptic events in electroencephalograms for a special kind of epilepsy called petit-mal epilepsy.
Martina Flammer
semanticscholar +1 more source
Homological properties of persistent homology
Journal of Algebra and Its ApplicationsIn this paper, we investigate to what extent persistent homology benefits from the properties of a homology theory. We show that persistent homology benefits from a Mayer–Vietoris sequence and a long exact sequence for a pair if one works with graded persistence modules.
Hani̇fe Varlı +2 more
openaire +4 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Gene Coexpression Network Comparison via Persistent Homology
International Journal of Genomics, 2018 Persistent homology, a topological data analysis (TDA) method, is applied to microarray data sets. Although there are a few papers referring to TDA methods in microarray analysis, the usage of persistent homology in the comparison of several weighted ...
Ali Nabi Duman, Harun Pirim
doaj +1 more source
Investigating rough single-fracture permeabilities with persistent homology [PDF]
Solid EarthThe permeability of rock fractures is a crucial parameter for flow processes in the subsurface. In the last few decades, different methods were developed to investigate on permeability in fractures, such as flow-through experiments, numerical flow ...
M. Fuchs, A. Suzuki, T. Hasumi, P. Blum
doaj +1 more source
Cluster Persistence for Weighted Graphs
Entropy, 2023 Persistent homology is a natural tool for probing the topological characteristics of weighted graphs, essentially focusing on their 0-dimensional homology.
Omer Bobrowski, Primoz Skraba
doaj +1 more source
Persistent Homology of Delay Embeddings [PDF]
, 2014 The objective of this study is to detect and quantify the periodic behavior of the signals using topological methods. We propose to use delay-coordinate embeddings as a tool to measure the periodicity of signals.
Emrani, Saba +2 more
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