Results 101 to 110 of about 1,043,448 (307)

Persistent Topological Laplacians—A Survey

open access: yesMathematics
Persistent topological Laplacians constitute a new class of tools in topological data analysis (TDA). They are motivated by the necessity to address challenges encountered in persistent homology when handling complex data.
Xiaoqi Wei, Guo-Wei Wei
doaj   +1 more source

Spatial Pyramid Bag of Words Algorithm Based on Persistent Homology [PDF]

open access: yesJisuanji kexue
To address the mismatch between the output form of topological features extracted from persistent homology and the common input form of machine learning algorithms,this paper proposes a new algorithmic framework-Spatial Pyramid Bag of Words Algorithm ...
YI Lisha, PENG Ningning
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Bot Detection on Social Networks Using Persistent Homology

open access: yesMathematical and Computational Applications, 2020
The growth of social media in recent years has contributed to an ever-increasing network of user data in every aspect of life. This volume of generated data is becoming a vital asset for the growth of companies and organizations as a powerful tool to ...
Minh Nguyen, Mehmet Aktas, Esra Akbas
doaj   +1 more source

Persistent Topology of Syntax [PDF]

open access: yes, 2015
We study the persistent homology of the data set of syntactic parameters of the world languages. We show that, while homology generators behave erratically over the whole data set, non-trivial persistent homology appears when one restricts to specific ...
Clark, John M.   +6 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Acute lymphoblastic leukemia classification using persistent homology

open access: yesThe European Physical Journal Special Topics
Acute Lymphoblastic Leukemia (ALL) is a prevalent form of childhood blood cancer characterized by the proliferation of immature white blood cells that rapidly replace normal cells in the bone marrow.
W. H. Shah   +5 more
semanticscholar   +1 more source

Persistent Homology Analysis for Solar Magnetograms

open access: yesThe Astrophysical Journal
Understanding the magnetic fields of the Sun is essential for unraveling the underlying mechanisms driving solar activity. Integrating topological data analysis techniques into these investigations can provide valuable insights into the intricate ...
P. Santamarina Guerrero   +3 more
doaj   +1 more source

Characterizing medium‐range order structure of binary silicate glasses using ring analysis and persistent homology

open access: yesJournal of The American Ceramic Society
Several fundamental questions about the medium‐range order (MRO) structure of oxide glasses remain unanswered. How do we define MRO in glass? Should we only consider the covalently bonded rings or also repeating patterns of non‐chemically bonded atom ...
Amirhossein F. Firooz   +3 more
semanticscholar   +1 more source

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