Results 121 to 130 of about 1,143,028 (268)

Persistent Homology and Persistent Cohomology: A Review

open access: yesEarthline Journal of Mathematical Sciences
Persistent homology is an important tool in non-linear data reduction. Its sister theory, persistent cohomology, has attracted less attention in the past years eventhough it has many advantages. Several literatures dealing with theory and computations of
Busayo Adeyege Okediji, A. Oladipo
semanticscholar   +1 more source

Stable volumes for persistent homology

open access: yesJournal of Applied and Computational Topology, 2023
AbstractThis paper proposes a stable volume and a stable volume variant, referred to as a stable sub-volume, for more reliable data analysis using persistent homology. In prior research, an optimal cycle and similar ideas have been proposed to identify the homological structure corresponding to each birth-death pair in a persistence diagram. While this
openaire   +3 more sources

Persistent homology of complex networks [PDF]

open access: yesJournal of Statistical Mechanics: Theory and Experiment, 2009
Long lived topological features are distinguished from short lived ones (considered as topological noise) in simplicial complexes constructed from complex networks. A new topological invariant, persistent homology, is determined and presented as a parametrized version of a Betti number.
Horak, Danijela   +2 more
openaire   +4 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

$P$-persistent homology of finite topological spaces [PDF]

open access: yes, 2015
Let $P$ be a finite poset. We will show that for any reasonable $P$-persistent object $X$ in the category of finite topological spaces, there is a $P-$ weighted graph, whose clique complex has the same $P$-persistent homology as $X$
Patania, Alice   +2 more
core   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

Predicting Affinity Through Homology (PATH): Interpretable binding affinity prediction with persistent homology.

open access: yesPLoS Computational Biology
Accurate binding affinity prediction (BAP) is crucial to structure-based drug design. We present PATH+, a novel, generalizable machine learning algorithm for BAP that exploits recent advances in computational topology.
Yuxi Long, Bruce R Donald
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Persistent Topology of Syntax [PDF]

open access: yes, 2015
We study the persistent homology of the data set of syntactic parameters of the world languages. We show that, while homology generators behave erratically over the whole data set, non-trivial persistent homology appears when one restricts to specific ...
Clark, John M.   +6 more
core  

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